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A novel approach to antigen-specific deletion of CTL with minimal cellular activation using alpha3 domain mutants of MHC class I/peptide complex.
Xu XN, Purbhoo MA, Chen N, Mongkolsapaya J, Cox JH, Meier UC, Tafuro S, Dunbar PR, Sewell AK, Hourigan CS, Appay V, Cerundolo V, Burrows SR, McMichael AJ, Screaton GR. Xu XN, et al. Among authors: appay v. Immunity. 2001 May;14(5):591-602. doi: 10.1016/s1074-7613(01)00133-9. Immunity. 2001. PMID: 11371361 Free article.
Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection.
Papagno L, Spina CA, Marchant A, Salio M, Rufer N, Little S, Dong T, Chesney G, Waters A, Easterbrook P, Dunbar PR, Shepherd D, Cerundolo V, Emery V, Griffiths P, Conlon C, McMichael AJ, Richman DD, Rowland-Jones SL, Appay V. Papagno L, et al. Among authors: appay v. PLoS Biol. 2004 Feb;2(2):E20. doi: 10.1371/journal.pbio.0020020. Epub 2004 Feb 17. PLoS Biol. 2004. PMID: 14966528 Free PMC article. Review.
HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor.
Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, Papagno L, Appay V, Weekes M, Conlon C, Spina C, Little S, Screaton G, van der Merwe A, Richman DD, McMichael AJ, Jones EY, Rowland-Jones SL. Dong T, et al. Among authors: appay v. J Exp Med. 2004 Dec 20;200(12):1547-57. doi: 10.1084/jem.20032044. Epub 2004 Dec 13. J Exp Med. 2004. PMID: 15596521 Free PMC article.
Memory CD8+ T cells in HIV infection.
McMichael AJ, Ogg G, Wilson J, Callan M, Hambleton S, Appay V, Kelleher T, Rowland-Jones S. McMichael AJ, et al. Among authors: appay v. Philos Trans R Soc Lond B Biol Sci. 2000 Mar 29;355(1395):363-7. doi: 10.1098/rstb.2000.0575. Philos Trans R Soc Lond B Biol Sci. 2000. PMID: 10794056 Free PMC article. Review.
Dynamics of T cell responses in HIV infection.
Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD, Rowland-Jones SL. Appay V, et al. J Immunol. 2002 Apr 1;168(7):3660-6. doi: 10.4049/jimmunol.168.7.3660. J Immunol. 2002. PMID: 11907132
Characterization of CD4(+) CTLs ex vivo.
Appay V, Zaunders JJ, Papagno L, Sutton J, Jaramillo A, Waters A, Easterbrook P, Grey P, Smith D, McMichael AJ, Cooper DA, Rowland-Jones SL, Kelleher AD. Appay V, et al. J Immunol. 2002 Jun 1;168(11):5954-8. doi: 10.4049/jimmunol.168.11.5954. J Immunol. 2002. PMID: 12023402
Mature CD8(+) T lymphocyte response to viral infection during fetal life.
Marchant A, Appay V, Van Der Sande M, Dulphy N, Liesnard C, Kidd M, Kaye S, Ojuola O, Gillespie GM, Vargas Cuero AL, Cerundolo V, Callan M, McAdam KP, Rowland-Jones SL, Donner C, McMichael AJ, Whittle H. Marchant A, et al. Among authors: appay v. J Clin Invest. 2003 Jun;111(11):1747-55. doi: 10.1172/JCI17470. J Clin Invest. 2003. PMID: 12782677 Free PMC article.
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