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Hydrolytically deficient MutS E694A is defective in the MutL-dependent activation of MutH and in the mismatch-dependent assembly of the MutS.MutL.heteroduplex complex.
Baitinger C, Burdett V, Modrich P. Baitinger C, et al. Among authors: modrich p. J Biol Chem. 2003 Dec 5;278(49):49505-11. doi: 10.1074/jbc.M308738200. Epub 2003 Sep 23. J Biol Chem. 2003. PMID: 14506224 Free article.
MutS E694A, in which Glu-694 of the Walker B motif is substituted with alanine, is defective in hydrolysis of bound ATP and has been reported to support MutL-dependent activation of the MutH d(GATC) endonuclease in a trans DNA activation assay (Junop, M. S., Obmolova, G., Rausch, …
MutS E694A, in which Glu-694 of the Walker B motif is substituted with alanine, is defective in hydrolysis of bound ATP and has been reporte …
Involvement of the beta clamp in methyl-directed mismatch repair in vitro.
Pluciennik A, Burdett V, Lukianova O, O'Donnell M, Modrich P. Pluciennik A, et al. Among authors: modrich p. J Biol Chem. 2009 Nov 20;284(47):32782-91. doi: 10.1074/jbc.M109.054528. Epub 2009 Sep 25. J Biol Chem. 2009. PMID: 19783657 Free PMC article.
We have confirmed previous findings that beta clamp interacts specifically with MutS and MutL (Lopez de Saro, F. J., Marinus, M. G., Modrich, P., and O'Donnell, M. (2006) J. Biol. Chem. 281, 14340-14349) and show that the mutator phenotype conferred by amino acid su …
We have confirmed previous findings that beta clamp interacts specifically with MutS and MutL (Lopez de Saro, F. J., Marinus, M. G., Modr …
Hydrolytic function of Exo1 in mammalian mismatch repair.
Shao H, Baitinger C, Soderblom EJ, Burdett V, Modrich P. Shao H, et al. Among authors: modrich p. Nucleic Acids Res. 2014 Jun;42(11):7104-12. doi: 10.1093/nar/gku420. Epub 2014 May 14. Nucleic Acids Res. 2014. PMID: 24829455 Free PMC article.
Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair.
Viswanathan M, Burdett V, Baitinger C, Modrich P, Lovett ST. Viswanathan M, et al. Among authors: modrich p. J Biol Chem. 2001 Aug 17;276(33):31053-8. doi: 10.1074/jbc.M105481200. Epub 2001 Jun 19. J Biol Chem. 2001. PMID: 11418610 Free article.
Previous biochemical analysis of Escherichia coli methyl-directed mismatch repair implicates three redundant single-strand DNA-specific exonucleases (RecJ, ExoI, and ExoVII) and at least one additional unknown exonuclease in the excision reaction (Cooper, D. L., Lahue, R. S., and …
Previous biochemical analysis of Escherichia coli methyl-directed mismatch repair implicates three redundant single-strand DNA-specific exon …
DNA mismatch repair: functions and mechanisms.
Iyer RR, Pluciennik A, Burdett V, Modrich PL. Iyer RR, et al. Chem Rev. 2006 Feb;106(2):302-23. doi: 10.1021/cr0404794. Chem Rev. 2006. PMID: 16464007 Review. No abstract available.
Assembly and molecular activities of the MutS tetramer.
Bjornson KP, Blackwell LJ, Sage H, Baitinger C, Allen D, Modrich P. Bjornson KP, et al. Among authors: modrich p. J Biol Chem. 2003 Sep 5;278(36):34667-73. doi: 10.1074/jbc.M305513200. Epub 2003 Jun 25. J Biol Chem. 2003. PMID: 12829697 Free article.
180 results