Utesch D - Search Results

1

Studies comparing in vivo:in vitro metabolism of three pharmaceutical compounds in rat, dog, monkey, and human using cryopreserved hepatocytes, microsomes, and collagen gel immobilized hepatocyte cultures.

Hewitt NJ, Bühring KU, Dasenbrock J, Haunschild J, Ladstetter B, Utesch D. Hewitt NJ, et al. Among authors: utesch d. Drug Metab Dispos. 2001 Jul;29(7):1042-50. Drug Metab Dispos. 2001. PMID: 11408372

2

Metabolic activity of fresh and cryopreserved cynomolgus monkey (Macaca fascicularis) hepatocytes.

Hewitt NJ, Fischer T, Zuehlke U, Oesch F, Utesch D. Hewitt NJ, et al. Among authors: utesch d. Xenobiotica. 2000 Jul;30(7):665-81. doi: 10.1080/00498250050077986. Xenobiotica. 2000. PMID: 10963058

3

Cryopreserved rat, dog and monkey hepatocytes: measurement of drug metabolizing enzymes in suspensions and cultures.

Hewitt NJ, Utesch D. Hewitt NJ, et al. Among authors: utesch d. Hum Exp Toxicol. 2004 Jun;23(6):307-16. doi: 10.1191/0960327104ht453oa. Hum Exp Toxicol. 2004. PMID: 15301157

4

Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo.

Reder-Hilz B, Ullrich M, Ringel M, Hewitt N, Utesch D, Oesch F, Hengstler JG. Reder-Hilz B, et al. Among authors: utesch d. Naunyn Schmiedebergs Arch Pharmacol. 2004 Apr;369(4):408-17. doi: 10.1007/s00210-004-0875-z. Epub 2004 Mar 4. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 14999438

5

Evaluation of the potential in vivo genotoxicity of quercetin.

Utesch D, Feige K, Dasenbrock J, Broschard TH, Harwood M, Danielewska-Nikiel B, Lines TC. Utesch D, et al. Mutat Res. 2008 Jun 30;654(1):38-44. doi: 10.1016/j.mrgentox.2008.04.008. Epub 2008 May 2. Mutat Res. 2008. PMID: 18556240

6

New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures.

Gebhardt R, Hengstler JG, Müller D, Glöckner R, Buenning P, Laube B, Schmelzer E, Ullrich M, Utesch D, Hewitt N, Ringel M, Hilz BR, Bader A, Langsch A, Koose T, Burger HJ, Maas J, Oesch F. Gebhardt R, et al. Among authors: utesch d. Drug Metab Rev. 2003 May-Aug;35(2-3):145-213. doi: 10.1081/dmr-120023684. Drug Metab Rev. 2003. PMID: 12959414 Review.

7

Metabolic activity of fresh and cryopreserved dog hepatocyte suspensions.

Swales NJ, Utesch D. Swales NJ, et al. Among authors: utesch d. Xenobiotica. 1998 Oct;28(10):937-48. doi: 10.1080/004982598239001. Xenobiotica. 1998. PMID: 9849641

8

Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction.

Hengstler JG, Utesch D, Steinberg P, Platt KL, Diener B, Ringel M, Swales N, Fischer T, Biefang K, Gerl M, Böttger T, Oesch F. Hengstler JG, et al. Among authors: utesch d. Drug Metab Rev. 2000 Feb;32(1):81-118. doi: 10.1081/dmr-100100564. Drug Metab Rev. 2000. PMID: 10711408 Review.

9

Phenol sulfotransferase activity in rat liver parenchymal cells cultured on collagen gels.

Utesch D, Oesch F. Utesch D, et al. Drug Metab Dispos. 1992 Jul-Aug;20(4):614-5. Drug Metab Dispos. 1992. PMID: 1356744 No abstract available.

10

Characterization of cryopreserved rat liver parenchymal cells by metabolism of diagnostic substrates and activities of related enzymes.

Utesch D, Diener B, Molitor E, Oesch F, Platt KL. Utesch D, et al. Biochem Pharmacol. 1992 Jul 22;44(2):309-15. doi: 10.1016/0006-2952(92)90014-a. Biochem Pharmacol. 1992. PMID: 1642645

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