Pinedo HM - Search Results

1

Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates.

Backus HH, Pinedo HM, Wouters D, Kuiper CM, Jansen G, van Groeningen CJ, Peters GJ. Backus HH, et al. Among authors: pinedo hm. Oncol Res. 2000;12(5):231-9. doi: 10.3727/096504001108747729. Oncol Res. 2000. PMID: 11417748

2

Purine nucleosides as cell-specific modulators of 5-fluorouracil metabolism and cytotoxicity.

Peters GJ, Laurensse E, Leyva A, Pinedo HM. Peters GJ, et al. Among authors: pinedo hm. Eur J Cancer Clin Oncol. 1987 Dec;23(12):1869-81. doi: 10.1016/0277-5379(87)90053-8. Eur J Cancer Clin Oncol. 1987. PMID: 3436351

3

Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil.

Peters GJ, van der Wilt CL, van Groeningen CJ, Smid K, Meijer S, Pinedo HM. Peters GJ, et al. Among authors: pinedo hm. J Clin Oncol. 1994 Oct;12(10):2035-42. doi: 10.1200/JCO.1994.12.10.2035. J Clin Oncol. 1994. PMID: 7931471 Clinical Trial.

4

Reversal of 5-fluorouracil-induced toxicity by oral administration of uridine.

van Groeningen CJ, Peters GJ, Pinedo HM. van Groeningen CJ, et al. Among authors: pinedo hm. Ann Oncol. 1993 Apr;4(4):317-20. doi: 10.1093/oxfordjournals.annonc.a058490. Ann Oncol. 1993. PMID: 8518223 Free article.

5

Screening of colon tumor cells and tissues for folylpolyglutamate synthetase activity.

van der Wilt CL, Cloos J, de Jong M, Pinedo HM, Peters GJ. van der Wilt CL, et al. Among authors: pinedo hm. Oncol Res. 1995;7(6):317-21. Oncol Res. 1995. PMID: 8527866

6

Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.

van Triest B, Pinedo HM, Telleman F, van der Wilt CL, Jansen G, Peters GJ. van Triest B, et al. Among authors: pinedo hm. Biochem Pharmacol. 1997 Jun 15;53(12):1855-66. doi: 10.1016/s0006-2952(97)82448-3. Biochem Pharmacol. 1997. PMID: 9256160

7

5-fluorouracil/leucovorin-induced inhibition of thymidylate synthase in normal tissues of mouse and man.

van der Wilt CL, van Groeningen CJ, Pinedo HM, Smid K, Hoekman K, Meijer S, Peters GJ. van der Wilt CL, et al. Among authors: pinedo hm. J Cancer Res Clin Oncol. 1997;123(11-12):595-601. doi: 10.1007/s004320050111. J Cancer Res Clin Oncol. 1997. PMID: 9620216

8

Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.

van Triest B, Pinedo HM, van Hensbergen Y, Smid K, Telleman F, Schoenmakers PS, van der Wilt CL, van Laar JA, Noordhuis P, Jansen G, Peters GJ. van Triest B, et al. Among authors: pinedo hm. Clin Cancer Res. 1999 Mar;5(3):643-54. Clin Cancer Res. 1999. PMID: 10100718

9

Experimental drugs and drug combinations in pancreatic cancer.

Kroep JR, Pinedo HM, van Groeningen CJ, Peters GJ. Kroep JR, et al. Among authors: pinedo hm. Ann Oncol. 1999;10 Suppl 4:234-8. Ann Oncol. 1999. PMID: 10436830 Review.

10

Determinants of activity of the antifolate thymidylate synthase inhibitors Tomudex (ZD1694) and GW1843U89 against mono- and multilayered colon cancer cell lines under folate-restricted conditions.

Peters GJ, Smitskamp-Wilms E, Smid K, Pinedo HM, Jansen G. Peters GJ, et al. Among authors: pinedo hm. Cancer Res. 1999 Nov 1;59(21):5529-35. Cancer Res. 1999. PMID: 10554030

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