Kaufman RJ - Search Results

1

Translational control is required for the unfolded protein response and in vivo glucose homeostasis.

Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. Mol Cell. 2001 Jun;7(6):1165-76. doi: 10.1016/s1097-2765(01)00265-9. Mol Cell. 2001. PMID: 11430820 Free article.

2

The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes.

Scheuner D, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. Endocr Rev. 2008 May;29(3):317-33. doi: 10.1210/er.2007-0039. Epub 2008 Apr 24. Endocr Rev. 2008. PMID: 18436705 Free PMC article. Review.

3

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ. Zhang K, et al. Among authors: kaufman rj. J Clin Invest. 2005 Feb;115(2):268-81. doi: 10.1172/JCI21848. J Clin Invest. 2005. PMID: 15690081 Free PMC article.

4

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis.

Scheuner D, Vander Mierde D, Song B, Flamez D, Creemers JW, Tsukamoto K, Ribick M, Schuit FC, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. Nat Med. 2005 Jul;11(7):757-64. doi: 10.1038/nm1259. Epub 2005 Jun 26. Nat Med. 2005. PMID: 15980866

5

The unfolded protein response in nutrient sensing and differentiation.

Kaufman RJ, Scheuner D, Schröder M, Shen X, Lee K, Liu CY, Arnold SM. Kaufman RJ, et al. Nat Rev Mol Cell Biol. 2002 Jun;3(6):411-21. doi: 10.1038/nrm829. Nat Rev Mol Cell Biol. 2002. PMID: 12042763 Review.

6

The unfolded protein response.

Liu CY, Kaufman RJ. Liu CY, et al. Among authors: kaufman rj. J Cell Sci. 2003 May 15;116(Pt 10):1861-2. doi: 10.1242/jcs.00408. J Cell Sci. 2003. PMID: 12692187 Review. No abstract available.

7

Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development.

Shen X, Ellis RE, Lee K, Liu CY, Yang K, Solomon A, Yoshida H, Morimoto R, Kurnit DM, Mori K, Kaufman RJ. Shen X, et al. Among authors: kaufman rj. Cell. 2001 Dec 28;107(7):893-903. doi: 10.1016/s0092-8674(01)00612-2. Cell. 2001. PMID: 11779465 Free article.

8

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress.

Wu J, Rutkowski DT, Dubois M, Swathirajan J, Saunders T, Wang J, Song B, Yau GD, Kaufman RJ. Wu J, et al. Among authors: kaufman rj. Dev Cell. 2007 Sep;13(3):351-64. doi: 10.1016/j.devcel.2007.07.005. Dev Cell. 2007. PMID: 17765679 Free article.

9

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.

Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ. Song B, et al. Among authors: kaufman rj. J Clin Invest. 2008 Oct;118(10):3378-89. doi: 10.1172/JCI34587. J Clin Invest. 2008. PMID: 18776938 Free PMC article.

10

Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells.

Back SH, Scheuner D, Han J, Song B, Ribick M, Wang J, Gildersleeve RD, Pennathur S, Kaufman RJ. Back SH, et al. Among authors: kaufman rj. Cell Metab. 2009 Jul;10(1):13-26. doi: 10.1016/j.cmet.2009.06.002. Cell Metab. 2009. PMID: 19583950 Free PMC article.

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