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The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain.
Purbhoo MA, Boulter JM, Price DA, Vuidepot AL, Hourigan CS, Dunbar PR, Olson K, Dawson SJ, Phillips RE, Jakobsen BK, Bell JI, Sewell AK. Purbhoo MA, et al. Among authors: phillips re. J Biol Chem. 2001 Aug 31;276(35):32786-92. doi: 10.1074/jbc.M102498200. Epub 2001 Jul 3. J Biol Chem. 2001. PMID: 11438524 Free article.
Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.
Sewell AK, Gerth UC, Price DA, Purbhoo MA, Boulter JM, Gao GF, Bell JI, Phillips RE, Jakobsen BK. Sewell AK, et al. Among authors: phillips re. Nat Med. 1999 Apr;5(4):399-404. doi: 10.1038/7398. Nat Med. 1999. PMID: 10202928
Human immunodeficiency virus-specific CD8(+) T-cell responses do not predict viral growth and clearance rates during structured intermittent antiretroviral therapy.
Oxenius A, McLean AR, Fischer M, Price DA, Dawson SJ, Hafner R, Schneider C, Joller H, Hirschel B, Phillips RE, Weber R, Günthard HF; Swiss HIV Cohort Study Group. Oxenius A, et al. Among authors: phillips re. J Virol. 2002 Oct;76(20):10169-76. doi: 10.1128/jvi.76.20.10169-10176.2002. J Virol. 2002. PMID: 12239291 Free PMC article.
264 results