Merritt EA - Search Results

1

A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity.

Aman AT, Fraser S, Merritt EA, Rodigherio C, Kenny M, Ahn M, Hol WG, Williams NA, Lencer WI, Hirst TR. Aman AT, et al. Among authors: merritt ea. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8536-41. doi: 10.1073/pnas.161273098. Epub 2001 Jul 10. Proc Natl Acad Sci U S A. 2001. PMID: 11447291 Free PMC article.

2

New insights into the structure-function relationships and therapeutic applications of cholera-like enterotoxins.

Hirst TR, Fraser S, Soriani M, Aman AT, de HL, Hearn A, Merritt E. Hirst TR, et al. Int J Med Microbiol. 2002 Feb;291(6-7):531-5. doi: 10.1078/1438-4221-00163. Int J Med Microbiol. 2002. PMID: 11890554 Review.

3

Structural studies of receptor binding by cholera toxin mutants.

Merritt EA, Sarfaty S, Jobling MG, Chang T, Holmes RK, Hirst TR, Hol WG. Merritt EA, et al. Protein Sci. 1997 Jul;6(7):1516-28. doi: 10.1002/pro.5560060716. Protein Sci. 1997. PMID: 9232653 Free PMC article.

4

Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.

Fan E, Merritt EA, Zhang Z, Pickens JC, Roach C, Ahn M, Hol WG. Fan E, et al. Among authors: merritt ea. Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):201-12. doi: 10.1107/s0907444900016814. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11173465

5

Characterization and crystal structure of a high-affinity pentavalent receptor-binding inhibitor for cholera toxin and E. coli heat-labile enterotoxin.

Merritt EA, Zhang Z, Pickens JC, Ahn M, Hol WG, Fan E. Merritt EA, et al. J Am Chem Soc. 2002 Jul 31;124(30):8818-24. doi: 10.1021/ja0202560. J Am Chem Soc. 2002. PMID: 12137534

6

Structural diversity in a conserved cholera toxin epitope involved in ganglioside binding.

Shoham M, Scherf T, Anglister J, Levitt M, Merritt EA, Hol WG. Shoham M, et al. Among authors: merritt ea. Protein Sci. 1995 May;4(5):841-8. doi: 10.1002/pro.5560040503. Protein Sci. 1995. PMID: 7545048 Free PMC article.

7

Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide.

Merritt EA, Sarfaty S, van den Akker F, L'Hoir C, Martial JA, Hol WG. Merritt EA, et al. Protein Sci. 1994 Feb;3(2):166-75. doi: 10.1002/pro.5560030202. Protein Sci. 1994. PMID: 8003954 Free PMC article.

8

Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.

Merritt EA, Sarfaty S, Chang TT, Palmer LM, Jobling MG, Holmes RK, Hol WG. Merritt EA, et al. Structure. 1995 Jun 15;3(6):561-70. doi: 10.1016/s0969-2126(01)00190-3. Structure. 1995. PMID: 8590017 Free article.

9

AB5 toxins.

Merritt EA, Hol WG. Merritt EA, et al. Curr Opin Struct Biol. 1995 Apr;5(2):165-71. doi: 10.1016/0959-440x(95)80071-9. Curr Opin Struct Biol. 1995. PMID: 7648317 Review.

10

Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT).

Merritt EA, Sixma TK, Kalk KH, van Zanten BA, Hol WG. Merritt EA, et al. Mol Microbiol. 1994 Aug;13(4):745-53. doi: 10.1111/j.1365-2958.1994.tb00467.x. Mol Microbiol. 1994. PMID: 7997185

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