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Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy.
Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, Pierson T, Smith K, Lisziewicz J, Lori F, Flexner C, Quinn TC, Chaisson RE, Rosenberg E, Walker B, Gange S, Gallant J, Siliciano RF. Finzi D, et al. Among authors: siliciano jd, siliciano rf. Nat Med. 1999 May;5(5):512-7. doi: 10.1038/8394. Nat Med. 1999. PMID: 10229227
Latency and viral persistence in HIV-1 infection.
Siliciano JD, Siliciano RF. Siliciano JD, et al. Among authors: siliciano rf. J Clin Invest. 2000 Oct;106(7):823-5. doi: 10.1172/JCI11246. J Clin Invest. 2000. PMID: 11018068 Free PMC article. No abstract available.
The multifactorial nature of HIV-1 latency.
Lassen K, Han Y, Zhou Y, Siliciano J, Siliciano RF. Lassen K, et al. Trends Mol Med. 2004 Nov;10(11):525-31. doi: 10.1016/j.molmed.2004.09.006. Trends Mol Med. 2004. PMID: 15519278 Review.
Recommendations for measuring HIV reservoir size in cure-directed clinical trials.
Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M, Alcami J, Hazuda D, Bushman F, Siliciano JD, Betts MR, Spivak AM, Planelles V, Hahn BH, Smith DM, Ho YC, Buzon MJ, Gaebler C, Paiardini M, Li Q, Estes JD, Hope TJ, Kostman J, Mounzer K, Caskey M, Fox L, Frank I, Riley JL, Tebas P, Montaner LJ; BEAT-HIV Delaney Collaboratory to Cure HIV-1 infection. Abdel-Mohsen M, et al. Among authors: siliciano jd, siliciano rf. Nat Med. 2020 Sep;26(9):1339-1350. doi: 10.1038/s41591-020-1022-1. Epub 2020 Sep 7. Nat Med. 2020. PMID: 32895573 Free PMC article. Review.
A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation.
Turk G, Seiger K, Lian X, Sun W, Parsons EM, Gao C, Rassadkina Y, Polo ML, Czernikier A, Ghiglione Y, Vellicce A, Varriale J, Lai J, Yuki Y, Martin M, Rhodes A, Lewin SR, Walker BD, Carrington M, Siliciano R, Siliciano J, Lichterfeld M, Laufer N, Yu XG. Turk G, et al. Ann Intern Med. 2022 Jan;175(1):95-100. doi: 10.7326/L21-0297. Epub 2021 Nov 16. Ann Intern Med. 2022. PMID: 34781719 Free PMC article.
Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient.
Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, Palmer S, Pilcher C, Pillai S, Price RW, Rothenberger M, Schacker T, Siliciano J, Siliciano R, Sinclair E, Strain M, Wong J, Richman D, Deeks SG. Yukl SA, et al. PLoS Pathog. 2013;9(5):e1003347. doi: 10.1371/journal.ppat.1003347. Epub 2013 May 9. PLoS Pathog. 2013. PMID: 23671416 Free PMC article. Clinical Trial.
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