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Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H Jr, Kneitz B, Lagaud G, Christ GJ, Edelmann W, Lisanti MP. Razani B, et al. Among authors: schubert w. J Biol Chem. 2001 Oct 12;276(41):38121-38. doi: 10.1074/jbc.M105408200. Epub 2001 Jul 16. J Biol Chem. 2001. PMID: 11457855 Free article.
Urogenital alterations in aged male caveolin-1 knockout mice.
Woodman SE, Cheung MW, Tarr M, North AC, Schubert W, Lagaud G, Marks CB, Russell RG, Hassan GS, Factor SM, Christ GJ, Lisanti MP. Woodman SE, et al. Among authors: schubert w. J Urol. 2004 Feb;171(2 Pt 1):950-7. doi: 10.1097/01.ju.0000105102.72295.b8. J Urol. 2004. PMID: 14713860
Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.
Park DS, Woodman SE, Schubert W, Cohen AW, Frank PG, Chandra M, Shirani J, Razani B, Tang B, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP. Park DS, et al. Among authors: schubert w. Am J Pathol. 2002 Jun;160(6):2207-17. doi: 10.1016/S0002-9440(10)61168-6. Am J Pathol. 2002. PMID: 12057923 Free PMC article.
481 results