Jensen RT - Search Results

1

Molecular basis for selectivity of high affinity peptide antagonists for the gastrin-releasing peptide receptor.

Tokita K, Katsuno T, Hocart SJ, Coy DH, Llinares M, Martinez J, Jensen RT. Tokita K, et al. Among authors: jensen rt. J Biol Chem. 2001 Sep 28;276(39):36652-63. doi: 10.1074/jbc.M104566200. Epub 2001 Aug 2. J Biol Chem. 2001. PMID: 11463790 Free article.

2

Importance of amino acids of the central portion of the second intracellular loop of the gastrin-releasing Peptide receptor for phospholipase C activation, internalization, and chronic down-regulation.

Schumann M, Nakagawa T, Mantey SA, Tokita K, Venzon DJ, Hocart SJ, Benya RV, Jensen RT. Schumann M, et al. Among authors: jensen rt. J Pharmacol Exp Ther. 2003 Nov;307(2):597-607. doi: 10.1124/jpet.103.055087. Epub 2003 Sep 11. J Pharmacol Exp Ther. 2003. PMID: 12970386

3

Development of high affinity camptothecin-bombesin conjugates that have targeted cytotoxicity for bombesin receptor-containing tumor cells.

Moody TW, Mantey SA, Pradhan TK, Schumann M, Nakagawa T, Martinez A, Fuselier J, Coy DH, Jensen RT. Moody TW, et al. Among authors: jensen rt. J Biol Chem. 2004 May 28;279(22):23580-9. doi: 10.1074/jbc.M401938200. Epub 2004 Mar 11. J Biol Chem. 2004. PMID: 15016826 Free article.

4

Identification of key amino acids in the gastrin-releasing peptide receptor (GRPR) responsible for high affinity binding of gastrin-releasing peptide (GRP).

Nakagawa T, Hocart SJ, Schumann M, Tapia JA, Mantey SA, Coy DH, Tokita K, Katsuno T, Jensen RT. Nakagawa T, et al. Among authors: jensen rt. Biochem Pharmacol. 2005 Feb 15;69(4):579-93. doi: 10.1016/j.bcp.2004.11.003. Epub 2004 Dec 23. Biochem Pharmacol. 2005. PMID: 15670577

5

Molecular basis for agonist selectivity and activation of the orphan bombesin receptor subtype 3 receptor.

Gonzalez N, Hocart SJ, Portal-Nuñez S, Mantey SA, Nakagawa T, Zudaire E, Coy DH, Jensen RT. Gonzalez N, et al. Among authors: jensen rt. J Pharmacol Exp Ther. 2008 Feb;324(2):463-74. doi: 10.1124/jpet.107.132332. Epub 2007 Nov 15. J Pharmacol Exp Ther. 2008. PMID: 18006692 Free PMC article.

6

The molecular basis for high affinity of a universal ligand for human bombesin receptor (BnR) family members.

Uehara H, Hocart SJ, González N, Mantey SA, Nakagawa T, Katsuno T, Coy DH, Jensen RT. Uehara H, et al. Among authors: jensen rt. Biochem Pharmacol. 2012 Oct 1;84(7):936-48. doi: 10.1016/j.bcp.2012.07.010. Epub 2012 Jul 22. Biochem Pharmacol. 2012. PMID: 22828605 Free PMC article.

7

Molecular basis of the selectivity of gastrin-releasing peptide receptor for gastrin-releasing peptide.

Tokita K, Hocart SJ, Coy DH, Jensen RT. Tokita K, et al. Among authors: jensen rt. Mol Pharmacol. 2002 Jun;61(6):1435-43. doi: 10.1124/mol.61.6.1435. Mol Pharmacol. 2002. PMID: 12021405

8

des-Met carboxyl-terminally modified analogues of bombesin function as potent bombesin receptor antagonists, partial agonists, or agonists.

Wang LH, Coy DH, Taylor JE, Jiang NY, Moreau JP, Huang SC, Frucht H, Haffar BM, Jensen RT. Wang LH, et al. Among authors: jensen rt. J Biol Chem. 1990 Sep 15;265(26):15695-703. J Biol Chem. 1990. PMID: 1697594 Free article.

9

Reduced peptide bond pseudopeptide analogues of secretin. A new class of secretin receptor antagonists.

Haffar BM, Hocart SJ, Coy DH, Mantey S, Chiang HC, Jensen RT. Haffar BM, et al. Among authors: jensen rt. J Biol Chem. 1991 Jan 5;266(1):316-22. J Biol Chem. 1991. PMID: 1702423 Free article.

10

Progress in the development of potent bombesin receptor antagonists.

Jensen RT, Coy DH. Jensen RT, et al. Trends Pharmacol Sci. 1991 Jan;12(1):13-9. doi: 10.1016/0165-6147(91)90483-9. Trends Pharmacol Sci. 1991. PMID: 1706545 Review.

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