Kezar HS - Search Results

1

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins.

Evans GB, Furneaux RH, Hutchison TL, Kezar HS, Morris PE Jr, Schramm VL, Tyler PC. Evans GB, et al. Among authors: kezar hs. J Org Chem. 2001 Aug 24;66(17):5723-30. doi: 10.1021/jo0155613. J Org Chem. 2001. PMID: 11511245

2

Synthesis and pharmacokinetic and pharmacodynamic evaluation of the forodesine HCl analog BCX-3040.

Kezar HS 3rd, Kilpatrick JM, Phillips D, Kellogg D, Zhang J, Morris PE Jr. Kezar HS 3rd, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1817-30. doi: 10.1080/15257770500267246. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438050

3

Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans.

Ananthan S, Kezar HS 3rd, Carter RL, Saini SK, Rice KC, Wells JL, Davis P, Xu H, Dersch CM, Bilsky EJ, Porreca F, Rothman RB. Ananthan S, et al. Among authors: kezar hs 3rd. J Med Chem. 1999 Sep 9;42(18):3527-38. doi: 10.1021/jm990039i. J Med Chem. 1999. PMID: 10479286

4

Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans.

Ananthan S, Kezar HS 3rd, Saini SK, Khare NK, Davis P, Dersch CM, Porreca F, Rothman RB. Ananthan S, et al. Among authors: kezar hs 3rd. Bioorg Med Chem Lett. 2003 Feb 10;13(3):529-32. doi: 10.1016/s0960-894x(02)00934-4. Bioorg Med Chem Lett. 2003. PMID: 12565965

5

Novel substituted pyrimidines as HCV replication (replicase) inhibitors.

Kwong CD, Clark JL, Fowler AT, Geng F, Kezar HS 3rd, Roychowdhury A, Reynolds RC, Maddry JA, Ananthan S, Secrist JA 3rd, Shih NY, Piwinski JJ, Li C, Feld B, Huang HC, Tong X, George Njoroge F, Arasappan A. Kwong CD, et al. Among authors: kezar hs 3rd. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1160-4. doi: 10.1016/j.bmcl.2011.11.091. Epub 2011 Dec 1. Bioorg Med Chem Lett. 2012. PMID: 22178556

6

Pyridofuran substituted pyrimidine derivatives as HCV replication (replicase) inhibitors.

Bennett F, Kezar HS 3rd, Girijavallabhan V, Huang Y, Huelgas R, Rossman R, Shih NY, Piwinski JJ, MacCoss M, Kwong CD, Clark JL, Fowler AT, Geng F, Roychowdhury A, Reynolds RC, Maddry JA, Ananthan S, Secrist JA 3rd, Li C, Chase R, Curry S, Huang HC, Tong X, George Njoroge F, Arasappan A. Bennett F, et al. Among authors: kezar hs 3rd. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5144-9. doi: 10.1016/j.bmcl.2012.06.021. Epub 2012 Jun 19. Bioorg Med Chem Lett. 2012. PMID: 22814211

7

Unique functional and structural properties of the LRRK2 protein ATP-binding pocket.

Liu Z, Galemmo RA Jr, Fraser KB, Moehle MS, Sen S, Volpicelli-Daley LA, DeLucas LJ, Ross LJ, Valiyaveettil J, Moukha-Chafiq O, Pathak AK, Ananthan S, Kezar H, White EL, Gupta V, Maddry JA, Suto MJ, West AB. Liu Z, et al. J Biol Chem. 2014 Nov 21;289(47):32937-51. doi: 10.1074/jbc.M114.602318. Epub 2014 Sep 16. J Biol Chem. 2014. PMID: 25228699 Free PMC article.

8

Synthesis and SAR of pyridothiazole substituted pyrimidine derived HCV replication inhibitors.

Girijavallabhan VM, Alvarez C, Bennett F, Chen L, Gavalas S, Huang Y, Kim SH, Kosinski A, Pinto P, Rizvi R, Rossman R, Shankar B, Tong L, Velazquez F, Venkatraman S, Verma VA, Kozlowski J, Shih NY, Piwinski JJ, MacCoss M, Kwong CD, Bansal N, Clark JL, Fowler AT, Kezar HS 3rd, Valiyaveettil J, Reynolds RC, Maddry JA, Ananthan S, Secrist JA 3rd, Li C, Chase R, Curry S, Huang HC, Tong X, Njoroge FG, Arasappan A. Girijavallabhan VM, et al. Among authors: kezar hs 3rd. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5652-7. doi: 10.1016/j.bmcl.2012.06.099. Epub 2012 Jul 15. Bioorg Med Chem Lett. 2012. PMID: 22858143

9

Synthesis and SAR of geminal substitutions at the C5' carbosugar position of pyrimidine-derived HCV inhibitors.

Verma VA, Rossman R, Bennett F, Chen L, Gavalas S, Girijavallabhan V, Huang Y, Kim SH, Kosinski A, Pinto P, Rizvi R, Shankar B, Tong L, Velazquez F, Venkatraman S, Kozlowski J, MacCoss M, Kwong CD, Bansal N, Kezar HS 3rd, Reynolds RC, Maddry JA, Ananthan S, Secrist JA 3rd, Li C, Chase R, Curry S, Huang HC, Tong X, Njoroge FG, Arasappan A. Verma VA, et al. Among authors: kezar hs 3rd. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6967-73. doi: 10.1016/j.bmcl.2012.08.111. Epub 2012 Sep 7. Bioorg Med Chem Lett. 2012. PMID: 23036957

10

5-Benzothiazole substituted pyrimidine derivatives as HCV replication (replicase) inhibitors.

Arasappan A, Bennett F, Girijavallabhan V, Huang Y, Huelgas R, Alvarez C, Chen L, Gavalas S, Kim SH, Kosinski A, Pinto P, Rizvi R, Rossman R, Shankar B, Tong L, Velazquez F, Venkatraman S, Verma VA, Kozlowski J, Shih NY, Piwinski JJ, MacCoss M, Kwong CD, Clark JL, Fowler AT, Geng F, Kezar HS 3rd, Roychowdhury A, Reynolds RC, Maddry JA, Ananthan S, Secrist JA 3rd, Li C, Chase R, Curry S, Huang HC, Tong X, Njoroge FG. Arasappan A, et al. Among authors: kezar hs 3rd. Bioorg Med Chem Lett. 2012 May 1;22(9):3229-34. doi: 10.1016/j.bmcl.2012.03.036. Epub 2012 Mar 13. Bioorg Med Chem Lett. 2012. PMID: 22472692

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

11 results

Search Page

Filters