Koo EH - Search Results

1

Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis.

Xia X, Qian S, Soriano S, Wu Y, Fletcher AM, Wang XJ, Koo EH, Wu X, Zheng H. Xia X, et al. Among authors: koo eh. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10863-8. doi: 10.1073/pnas.191284198. Epub 2001 Aug 21. Proc Natl Acad Sci U S A. 2001. PMID: 11517342 Free PMC article.

2

The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms.

Xia X, Wang P, Sun X, Soriano S, Shum WK, Yamaguchi H, Trumbauer ME, Takashima A, Koo EH, Zheng H. Xia X, et al. Among authors: koo eh. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8760-5. doi: 10.1073/pnas.132045399. Epub 2002 Jun 17. Proc Natl Acad Sci U S A. 2002. PMID: 12070348 Free PMC article.

3

Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis.

Kang DE, Soriano S, Xia X, Eberhart CG, De Strooper B, Zheng H, Koo EH. Kang DE, et al. Among authors: koo eh. Cell. 2002 Sep 20;110(6):751-62. doi: 10.1016/s0092-8674(02)00970-4. Cell. 2002. PMID: 12297048 Free article.

4

The amyloid precursor protein: beyond amyloid.

Zheng H, Koo EH. Zheng H, et al. Among authors: koo eh. Mol Neurodegener. 2006 Jul 3;1:5. doi: 10.1186/1750-1326-1-5. Mol Neurodegener. 2006. PMID: 16930452 Free PMC article.

5

Biology and pathophysiology of the amyloid precursor protein.

Zheng H, Koo EH. Zheng H, et al. Among authors: koo eh. Mol Neurodegener. 2011 Apr 28;6(1):27. doi: 10.1186/1750-1326-6-27. Mol Neurodegener. 2011. PMID: 21527012 Free PMC article.

6

Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing.

Soriano S, Kang DE, Fu M, Pestell R, Chevallier N, Zheng H, Koo EH. Soriano S, et al. Among authors: koo eh. J Cell Biol. 2001 Feb 19;152(4):785-94. doi: 10.1083/jcb.152.4.785. J Cell Biol. 2001. PMID: 11266469 Free PMC article.

7

Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway.

Kang DE, Soriano S, Frosch MP, Collins T, Naruse S, Sisodia SS, Leibowitz G, Levine F, Koo EH. Kang DE, et al. Among authors: koo eh. J Neurosci. 1999 Jun 1;19(11):4229-37. doi: 10.1523/JNEUROSCI.19-11-04229.1999. J Neurosci. 1999. PMID: 10341227 Free PMC article.

8

Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation.

Chevallier NL, Soriano S, Kang DE, Masliah E, Hu G, Koo EH. Chevallier NL, et al. Among authors: koo eh. Am J Pathol. 2005 Jul;167(1):151-9. doi: 10.1016/S0002-9440(10)62962-8. Am J Pathol. 2005. PMID: 15972961 Free PMC article.

9

Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex.

Baki L, Marambaud P, Efthimiopoulos S, Georgakopoulos A, Wen P, Cui W, Shioi J, Koo E, Ozawa M, Friedrich VL Jr, Robakis NK. Baki L, et al. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2381-6. doi: 10.1073/pnas.041603398. Proc Natl Acad Sci U S A. 2001. PMID: 11226248 Free PMC article.

10

The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.

Saura CA, Tomita T, Soriano S, Takahashi M, Leem JY, Honda T, Koo EH, Iwatsubo T, Thinakaran G. Saura CA, et al. Among authors: koo eh. J Biol Chem. 2000 Jun 2;275(22):17136-42. doi: 10.1074/jbc.M909624199. J Biol Chem. 2000. PMID: 10748144 Free article.

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