Vårum KM - Search Results

1

Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo.

Köping-Höggård M, Tubulekas I, Guan H, Edwards K, Nilsson M, Vårum KM, Artursson P. Köping-Höggård M, et al. Among authors: varum km. Gene Ther. 2001 Jul;8(14):1108-21. doi: 10.1038/sj.gt.3301492. Gene Ther. 2001. PMID: 11526458

2

Targeted gene delivery with trisaccharide-substituted chitosan oligomers in vitro and after lung administration in vivo.

Issa MM, Köping-Höggård M, Tømmeraas K, Vårum KM, Christensen BE, Strand SP, Artursson P. Issa MM, et al. Among authors: varum km. J Control Release. 2006 Sep 28;115(1):103-12. doi: 10.1016/j.jconrel.2006.06.029. Epub 2006 Jul 1. J Control Release. 2006. PMID: 16901570

3

A miniaturized nebulization catheter for improved gene delivery to the mouse lung.

Köping-Höggård M, Issa MM, Köhler T, Tronde A, Vårum KM, Artursson P. Köping-Höggård M, et al. Among authors: varum km. J Gene Med. 2005 Sep;7(9):1215-22. doi: 10.1002/jgm.762. J Gene Med. 2005. PMID: 15895386

4

Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers.

Köping-Höggård M, Vårum KM, Issa M, Danielsen S, Christensen BE, Stokke BT, Artursson P. Köping-Höggård M, et al. Among authors: varum km. Gene Ther. 2004 Oct;11(19):1441-52. doi: 10.1038/sj.gt.3302312. Gene Ther. 2004. PMID: 15269712

5

Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo.

Köping-Höggård M, Mel'nikova YS, Vårum KM, Lindman B, Artursson P. Köping-Höggård M, et al. Among authors: varum km. J Gene Med. 2003 Feb;5(2):130-41. doi: 10.1002/jgm.327. J Gene Med. 2003. PMID: 12539151

6

Chitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells.

Schipper NG, Vårum KM, Artursson P. Schipper NG, et al. Among authors: varum km. Pharm Res. 1996 Nov;13(11):1686-92. doi: 10.1023/a:1016444808000. Pharm Res. 1996. PMID: 8956335

7

Chitosans as absorption enhancers for poorly absorbable drugs 2: mechanism of absorption enhancement.

Schipper NG, Olsson S, Hoogstraate JA, deBoer AG, Vårum KM, Artursson P. Schipper NG, et al. Among authors: varum km. Pharm Res. 1997 Jul;14(7):923-9. doi: 10.1023/a:1012160102740. Pharm Res. 1997. PMID: 9244151

8

Chitosans as absorption enhancers of poorly absorbable drugs. 3: Influence of mucus on absorption enhancement.

Schipper NG, Vârum KM, Stenberg P, Ocklind G, Lennernäs H, Artursson P. Schipper NG, et al. Among authors: varum km. Eur J Pharm Sci. 1999 Aug;8(4):335-43. doi: 10.1016/s0928-0987(99)00032-9. Eur J Pharm Sci. 1999. PMID: 10425384

9

Tailoring of chitosans for gene delivery: novel self-branched glycosylated chitosan oligomers with improved functional properties.

Strand SP, Issa MM, Christensen BE, Vårum KM, Artursson P. Strand SP, et al. Among authors: varum km. Biomacromolecules. 2008 Nov;9(11):3268-76. doi: 10.1021/bm800832u. Epub 2008 Oct 4. Biomacromolecules. 2008. PMID: 18834173

10

Molecular design of chitosan gene delivery systems with an optimized balance between polyplex stability and polyplex unpacking.

Strand SP, Lelu S, Reitan NK, de Lange Davies C, Artursson P, Vårum KM. Strand SP, et al. Among authors: varum km. Biomaterials. 2010 Feb;31(5):975-87. doi: 10.1016/j.biomaterials.2009.09.102. Epub 2009 Oct 25. Biomaterials. 2010. PMID: 19857892

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