Bowen DT - Search Results

1

The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials.

Kottaridis PD, Gale RE, Frew ME, Harrison G, Langabeer SE, Belton AA, Walker H, Wheatley K, Bowen DT, Burnett AK, Goldstone AH, Linch DC. Kottaridis PD, et al. Among authors: bowen dt. Blood. 2001 Sep 15;98(6):1752-9. doi: 10.1182/blood.v98.6.1752. Blood. 2001. PMID: 11535508 Free article. Clinical Trial.

2

Two new polymorphisms but no mutations of the KIT gene in patients with myelodysplasia at positions corresponding to human FMS and murine W locus mutational hot spots.

Bowen DT, Padua RA, Burnett AK, deCastro CM, Kaufman RE. Bowen DT, et al. Leukemia. 1993 Nov;7(11):1883-5. Leukemia. 1993. PMID: 7694008

3

Refractory anaemia with preleukaemic polyclonal haemopoiesis and the emergence of monoclonal erythropoiesis on disease progression.

Culligan DJ, Bowen DT, May A, White D, Padua RA, Burnett AK. Culligan DJ, et al. Among authors: bowen dt. Br J Haematol. 1995 Mar;89(3):675-7. doi: 10.1111/j.1365-2141.1995.tb08389.x. Br J Haematol. 1995. PMID: 7734379

4

Mutant RAS selectively promotes sensitivity of myeloid leukemia cells to apoptosis by a protein kinase C-dependent process.

Gallagher AP, Burnett AK, Bowen DT, Darley RL. Gallagher AP, et al. Among authors: bowen dt. Cancer Res. 1998 May 1;58(9):2029-35. Cancer Res. 1998. PMID: 9581849

5

Cytogenetic abnormalities in the myelodysplastic syndromes and occupational or environmental exposure.

West RR, Stafford DA, White AD, Bowen DT, Padua RA. West RR, et al. Among authors: bowen dt. Blood. 2000 Mar 15;95(6):2093-7. Blood. 2000. PMID: 10706879 Free article.

6

Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors.

Kottaridis PD, Gale RE, Langabeer SE, Frew ME, Bowen DT, Linch DC. Kottaridis PD, et al. Among authors: bowen dt. Blood. 2002 Oct 1;100(7):2393-8. doi: 10.1182/blood-2002-02-0420. Blood. 2002. PMID: 12239147 Free article.

7

CYP1A1*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication.

Bowen DT, Frew ME, Rollinson S, Roddam PL, Dring A, Smith MT, Langabeer SE, Morgan GJ. Bowen DT, et al. Blood. 2003 Apr 1;101(7):2770-4. doi: 10.1182/blood-2002-01-0228. Epub 2002 Dec 5. Blood. 2003. PMID: 12468438 Free article.

8

Antioxidant enzyme expression in myelodysplastic and acute myeloid leukemia bone marrow: further evidence of a pathogenetic role for oxidative stress?

Bowen D, Wang L, Frew M, Kerr R, Groves M. Bowen D, et al. Haematologica. 2003 Sep;88(9):1070-2. Haematologica. 2003. PMID: 12969817 No abstract available.

9

Second hit mutations in the RTK/RAS signaling pathway in acute myeloid leukemia with inv(16).

Valk PJ, Bowen DT, Frew ME, Goodeve AC, Löwenberg B, Reilly JT. Valk PJ, et al. Among authors: bowen dt. Haematologica. 2004 Jan;89(1):106. Haematologica. 2004. PMID: 14754614 No abstract available.

10

Mutations in PTPN11 are uncommon in adult myelodysplastic syndromes and acute myeloid leukaemia.

Johan MF, Bowen DT, Frew ME, Goodeve AC, Wilson GA, Peake IR, Reilly JT. Johan MF, et al. Among authors: bowen dt. Br J Haematol. 2004 Mar;124(6):843-4. doi: 10.1111/j.1365-2141.2004.04862.x. Br J Haematol. 2004. PMID: 15009076 Free article. No abstract available.

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