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Page 1
Identification of E2F-1/Cyclin A antagonists.
Sharma SK, Ramsey TM, Chen YN, Chen W, Martin MS, Clune K, Sabio M, Bair KW. Sharma SK, et al. Among authors: bair kw. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2449-52. doi: 10.1016/s0960-894x(01)00486-3. Bioorg Med Chem Lett. 2001. PMID: 11549444
Protein-protein interactions: lessons learned.
Sharma SK, Ramsey TM, Bair KW. Sharma SK, et al. Among authors: bair kw. Curr Med Chem Anticancer Agents. 2002 Mar;2(2):311-30. doi: 10.2174/1568011023354191. Curr Med Chem Anticancer Agents. 2002. PMID: 12678748 Review.
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).
Remiszewski SW, Sambucetti LC, Bair KW, Bontempo J, Cesarz D, Chandramouli N, Chen R, Cheung M, Cornell-Kennon S, Dean K, Diamantidis G, France D, Green MA, Howell KL, Kashi R, Kwon P, Lassota P, Martin MS, Mou Y, Perez LB, Sharma S, Smith T, Sorensen E, Taplin F, Trogani N, Versace R, Walker H, Weltchek-Engler S, Wood A, Wu A, Atadja P. Remiszewski SW, et al. Among authors: bair kw. J Med Chem. 2003 Oct 9;46(21):4609-24. doi: 10.1021/jm030235w. J Med Chem. 2003. PMID: 14521422
Solid-phase total synthesis of polymyxin B1.
Sharma SK, Wu AD, Chandramouli N, Fotsch C, Kardash G, Bair KW. Sharma SK, et al. Among authors: bair kw. J Pept Res. 1999 May;53(5):501-6. doi: 10.1034/j.1399-3011.1999.00045.x. J Pept Res. 1999. PMID: 10424344
Synthesis and antitumor activity of ester-modified analogues of bengamide B.
Kinder FR Jr, Versace RW, Bair KW, Bontempo JM, Cesarz D, Chen S, Crews P, Czuchta AM, Jagoe CT, Mou Y, Nemzek R, Phillips PE, Tran LD, Wang RM, Weltchek S, Zabludoff S. Kinder FR Jr, et al. Among authors: bair kw. J Med Chem. 2001 Oct 25;44(22):3692-9. doi: 10.1021/jm010188c. J Med Chem. 2001. PMID: 11606134
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
Zheng X, Bauer P, Baumeister T, Buckmelter AJ, Caligiuri M, Clodfelter KH, Han B, Ho YC, Kley N, Lin J, Reynolds DJ, Sharma G, Smith CC, Wang Z, Dragovich PS, Oh A, Wang W, Zak M, Gunzner-Toste J, Zhao G, Yuen PW, Bair KW. Zheng X, et al. Among authors: bair kw. J Med Chem. 2013 Jun 27;56(12):4921-37. doi: 10.1021/jm400186h. Epub 2013 Jun 13. J Med Chem. 2013. PMID: 23617784
Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Dragovich PS, Bair KW, Baumeister T, Ho YC, Liederer BM, Liu X, Liu Y, O'Brien T, Oeh J, Sampath D, Skelton N, Wang L, Wang W, Wu H, Xiao Y, Yuen PW, Zak M, Zhang L, Zheng X. Dragovich PS, et al. Among authors: bair kw. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4875-85. doi: 10.1016/j.bmcl.2013.06.090. Epub 2013 Jul 6. Bioorg Med Chem Lett. 2013. PMID: 23899614
Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).
Martin MW, Lancia DR Jr, Li H, Schiller SER, Toms AV, Wang Z, Bair KW, Castro J, Fessler S, Gotur D, Hubbs SE, Kauffman GS, Kershaw M, Luke GP, McKinnon C, Yao L, Lu W, Millan DS. Martin MW, et al. Among authors: bair kw. Bioorg Med Chem Lett. 2019 Apr 15;29(8):1001-1006. doi: 10.1016/j.bmcl.2019.02.012. Epub 2019 Feb 11. Bioorg Med Chem Lett. 2019. PMID: 30803804
44 results