Taylor C - Search Results

1

Brain microdialysis and PK/PD correlation of pregabalin in rats.

Feng MR, Turluck D, Burleigh J, Lister R, Fan C, Middlebrook A, Taylor C, Su T. Feng MR, et al. Among authors: taylor c. Eur J Drug Metab Pharmacokinet. 2001 Jan-Jun;26(1-2):123-8. doi: 10.1007/BF03190385. Eur J Drug Metab Pharmacokinet. 2001. PMID: 11554426

2

Novel cyclopropyl beta-amino acid analogues of pregabalin and gabapentin that target the alpha2-delta protein.

Schwarz JB, Gibbons SE, Graham SR, Colbry NL, Guzzo PR, Le VD, Vartanian MG, Kinsora JJ, Lotarski SM, Li Z, Dickerson MR, Su TZ, Weber ML, El-Kattan A, Thorpe AJ, Donevan SD, Taylor CP, Wustrow DJ. Schwarz JB, et al. J Med Chem. 2005 Apr 21;48(8):3026-35. doi: 10.1021/jm0491086. J Med Chem. 2005. PMID: 15828841

3

Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA.

Goldlust A, Su TZ, Welty DF, Taylor CP, Oxender DL. Goldlust A, et al. Among authors: taylor cp. Epilepsy Res. 1995 Sep;22(1):1-11. doi: 10.1016/0920-1211(95)00028-9. Epilepsy Res. 1995. PMID: 8565962

4

A summary of mechanistic hypotheses of gabapentin pharmacology.

Taylor CP, Gee NS, Su TZ, Kocsis JD, Welty DF, Brown JP, Dooley DJ, Boden P, Singh L. Taylor CP, et al. Epilepsy Res. 1998 Feb;29(3):233-49. doi: 10.1016/s0920-1211(97)00084-3. Epilepsy Res. 1998. PMID: 9551785 Review.

5

The discovery of [1-(4-dimethylamino-benzyl)-piperidin-4-yl]-[4-(3,3-dimethylbutyl)-phen yl]-(3-methyl-but-2-enyl)-amine, an N-type Ca+2 channel blocker with oral activity for analgesia.

Hu LY, Ryder TR, Rafferty MF, Taylor CP, Feng MR, Kuo BS, Lotarski SM, Miljanich GP, Millerman E, Siebers KM, Szoke BG. Hu LY, et al. Among authors: taylor cp. Bioorg Med Chem. 2000 Jun;8(6):1203-12. doi: 10.1016/s0968-0896(00)00077-8. Bioorg Med Chem. 2000. PMID: 10896101

6

Neuronal N-type calcium channel blockers: a series of 4-piperidinylaniline analogs with analgesic activity.

Hu LY, Ryder TR, Rafferty MF, Siebers KM, Malone T, Chatterjee A, Feng MR, Lotarski SM, Rock DM, Stoehr SJ, Taylor CP, Weber ML, Miljanich GP, Millerman E, Szoke BG. Hu LY, et al. Among authors: taylor cp. Drug Des Discov. 2000;17(1):85-93. Drug Des Discov. 2000. PMID: 10928451

7

Activity profile of pregabalin in rodent models of epilepsy and ataxia.

Vartanian MG, Radulovic LL, Kinsora JJ, Serpa KA, Vergnes M, Bertram E, Taylor CP. Vartanian MG, et al. Epilepsy Res. 2006 Mar;68(3):189-205. doi: 10.1016/j.eplepsyres.2005.11.001. Epub 2005 Dec 5. Epilepsy Res. 2006. PMID: 16337109

8

Gabapentin anticonvulsant action in rats: disequilibrium with peak drug concentrations in plasma and brain microdialysate.

Welty DF, Schielke GP, Vartanian MG, Taylor CP. Welty DF, et al. Among authors: taylor cp. Epilepsy Res. 1993 Dec;16(3):175-81. doi: 10.1016/0920-1211(93)90078-l. Epilepsy Res. 1993. PMID: 8119268

9

Pregabalin is a potent and selective ligand for α(2)δ-1 and α(2)δ-2 calcium channel subunits.

Li Z, Taylor CP, Weber M, Piechan J, Prior F, Bian F, Cui M, Hoffman D, Donevan S. Li Z, et al. Eur J Pharmacol. 2011 Sep 30;667(1-3):80-90. doi: 10.1016/j.ejphar.2011.05.054. Epub 2011 Jun 1. Eur J Pharmacol. 2011. PMID: 21651903

10

Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.

Hu LY, Ryder TR, Rafferty MF, Feng MR, Lotarski SM, Rock DM, Sinz M, Stoehr SJ, Taylor CP, Weber ML, Bowersox SS, Miljanich GP, Millerman E, Wang YX, Szoke BG. Hu LY, et al. Among authors: taylor cp. J Med Chem. 1999 Oct 7;42(20):4239-49. doi: 10.1021/jm9902739. J Med Chem. 1999. PMID: 10514294

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