Flanders K - Search Results

1

Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis.

Im YH, Kim HT, Kim IY, Factor VM, Hahm KB, Anzano M, Jang JJ, Flanders K, Haines DC, Thorgeirsson SS, Sizeland A, Kim SJ. Im YH, et al. Among authors: flanders k. Cancer Res. 2001 Sep 15;61(18):6665-8. Cancer Res. 2001. PMID: 11559531

2

Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin.

Flanders KC, Major CD, Arabshahi A, Aburime EE, Okada MH, Fujii M, Blalock TD, Schultz GS, Sowers A, Anzano MA, Mitchell JB, Russo A, Roberts AB. Flanders KC, et al. Am J Pathol. 2003 Dec;163(6):2247-57. doi: 10.1016/s0002-9440(10)63582-1. Am J Pathol. 2003. PMID: 14633599 Free PMC article.

3

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation.

Flanders KC, Sullivan CD, Fujii M, Sowers A, Anzano MA, Arabshahi A, Major C, Deng C, Russo A, Mitchell JB, Roberts AB. Flanders KC, et al. Am J Pathol. 2002 Mar;160(3):1057-68. doi: 10.1016/S0002-9440(10)64926-7. Am J Pathol. 2002. PMID: 11891202 Free PMC article.

4

Definition of smad3 phosphorylation events that affect malignant and metastatic behaviors in breast cancer cells.

Bae E, Sato M, Kim RJ, Kwak MK, Naka K, Gim J, Kadota M, Tang B, Flanders KC, Kim TA, Leem SH, Park T, Liu F, Wakefield LM, Kim SJ, Ooshima A. Bae E, et al. Among authors: flanders kc. Cancer Res. 2014 Nov 1;74(21):6139-49. doi: 10.1158/0008-5472.CAN-14-0803. Epub 2014 Sep 9. Cancer Res. 2014. PMID: 25205100 Free PMC article.

5

Endocrine expression of the active form of TGF-beta1 in the TGF-beta1 null mice fails to ameliorate lethal phenotype.

Longenecker G, Thyagarajan T, Nagineni CN, Flanders KC, Factor V, Miller G, Ward JM, Nalca A, Rangnekar VM, Thorgeirsson S, Kulkarni AB. Longenecker G, et al. Cytokine. 2002 Apr 7;18(1):43-50. doi: 10.1006/cyto.2002.1025. Cytokine. 2002. PMID: 12090759

6

Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway.

Bian Y, Terse A, Du J, Hall B, Molinolo A, Zhang P, Chen W, Flanders KC, Gutkind JS, Wakefield LM, Kulkarni AB. Bian Y, et al. Cancer Res. 2009 Jul 15;69(14):5918-26. doi: 10.1158/0008-5472.CAN-08-4623. Epub 2009 Jul 7. Cancer Res. 2009. PMID: 19584284 Free PMC article.

7

Medical applications of transforming growth factor-beta.

Flanders KC, Burmester JK. Flanders KC, et al. Clin Med Res. 2003 Jan;1(1):13-20. doi: 10.3121/cmr.1.1.13. Clin Med Res. 2003. PMID: 15931280 Free PMC article. Review.

8

Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression.

Kohn EA, Yang YA, Du Z, Nagano Y, Van Schyndle CM, Herrmann MA, Heldman M, Chen JQ, Stuelten CH, Flanders KC, Wakefield LM. Kohn EA, et al. Mol Cancer Res. 2012 Oct;10(10):1389-99. doi: 10.1158/1541-7786.MCR-12-0136-T. Epub 2012 Aug 9. Mol Cancer Res. 2012. PMID: 22878587 Free PMC article.

9

Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics.

Figueroa JD, Flanders KC, Garcia-Closas M, Anderson WF, Yang XR, Matsuno RK, Duggan MA, Pfeiffer RM, Ooshima A, Cornelison R, Gierach GL, Brinton LA, Lissowska J, Peplonska B, Wakefield LM, Sherman ME. Figueroa JD, et al. Among authors: flanders kc. Breast Cancer Res Treat. 2010 Jun;121(3):727-35. doi: 10.1007/s10549-009-0590-z. Epub 2009 Nov 24. Breast Cancer Res Treat. 2010. PMID: 19937272 Free PMC article.

10

The Outcome of TGFβ Antagonism in Metastatic Breast Cancer Models In Vivo Reflects a Complex Balance between Tumor-Suppressive and Proprogression Activities of TGFβ.

Yang Y, Yang HH, Tang B, Wu AML, Flanders KC, Moshkovich N, Weinberg DS, Welsh MA, Weng J, Ochoa HJ, Hu TY, Herrmann MA, Chen J, Edmondson EF, Simpson RM, Liu F, Liu H, Lee MP, Wakefield LM. Yang Y, et al. Clin Cancer Res. 2020 Feb 1;26(3):643-656. doi: 10.1158/1078-0432.CCR-19-2370. Epub 2019 Oct 3. Clin Cancer Res. 2020. PMID: 31582516 Free PMC article.

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