Naguib FN - Search Results

1

Modulation of the pharmacokinetics of endogenous plasma uridine by 5-(phenylthio)acyclouridine, a uridine phosphorylase inhibitor: implications for chemotherapy.

Al Safarjalani ON, Zhou XJ, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Al Safarjalani ON, et al. Among authors: naguib fn. Cancer Chemother Pharmacol. 2001 Aug;48(2):145-50. doi: 10.1007/s002800100292. Cancer Chemother Pharmacol. 2001. PMID: 11565561

2

5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability: relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens.

Al Safarjalani ON, Zhou XJ, Rais RH, Shi J, Schinazi RF, Naguib FN, El Kouni MH. Al Safarjalani ON, et al. Among authors: naguib fn. Cancer Chemother Pharmacol. 2005 Jun;55(6):541-51. doi: 10.1007/s00280-004-0967-y. Epub 2005 Feb 24. Cancer Chemother Pharmacol. 2005. PMID: 15729584

3

Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor.

Al Safarjalani ON, Rais R, Shi J, Schinazi RF, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Among authors: naguib fn. Cancer Chemother Pharmacol. 2006 Nov;58(5):692-8. doi: 10.1007/s00280-006-0213-x. Epub 2006 Mar 10. Cancer Chemother Pharmacol. 2006. PMID: 16528530

4

Suppression of thymidine phosphorylase expression by promoter methylation in human cancer cells lacking enzyme activity.

Guarcello V, Blanquicett C, Naguib FN, El Kouni MH. Guarcello V, et al. Among authors: naguib fn. Cancer Chemother Pharmacol. 2008 Jun;62(1):85-96. doi: 10.1007/s00280-007-0578-5. Epub 2007 Sep 1. Cancer Chemother Pharmacol. 2008. PMID: 17805539

5

Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity.

Al Safarjalani ON, Rais R, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Among authors: naguib fn. Cancer Chemother Pharmacol. 2012 Jun;69(6):1449-55. doi: 10.1007/s00280-012-1842-x. Epub 2012 Feb 29. Cancer Chemother Pharmacol. 2012. PMID: 22373605

6

Enhancement of 5-fluoro-2'-deoxyuridine antitumor efficacy by the uridine phosphorylase inhibitor 5-(benzyloxybenzyl)barbituric acid acyclonucleoside.

Ashour OM, Naguib FN, Khalifa MM, Abdel-Raheem MH, Panzica RP, el Kouni MH. Ashour OM, et al. Among authors: naguib fn. Cancer Res. 1995 Mar 1;55(5):1092-8. Cancer Res. 1995. PMID: 7866994

7

5-Benzylbarbituric acid derivatives, potent and specific inhibitors of uridine phosphorylase.

Naguib FN, Levesque DL, Wang EC, Panzica RP, el Kouni MH. Naguib FN, et al. Biochem Pharmacol. 1993 Oct 5;46(7):1273-83. doi: 10.1016/0006-2952(93)90477-e. Biochem Pharmacol. 1993. PMID: 8216379

8

5-(m-Benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2',3',5'-tri-O-acetyluridine, a prodrug of uridine, as modulators of plasma uridine concentration. Implications for chemotherapy.

Ashour OM, Naguib FN, el Kouni MH. Ashour OM, et al. Among authors: naguib fn. Biochem Pharmacol. 1996 Jun 28;51(12):1601-11. doi: 10.1016/0006-2952(96)00102-5. Biochem Pharmacol. 1996. PMID: 8687475

9

Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii.

el Kouni MH, Naguib FN, Panzica RP, Otter BA, Chu SH, Gosselin G, Chu CK, Schinazi RF, Shealy YF, Goudgaon N, Ozerov AA, Ueda T, Iltzsch MH. el Kouni MH, et al. Among authors: naguib fn. Biochem Pharmacol. 1996 Jun 28;51(12):1687-700. doi: 10.1016/0006-2952(96)00213-4. Biochem Pharmacol. 1996. PMID: 8687484

10

Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase: relevance to chemotherapy.

Ashour OM, Al Safarjalani ON, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Ashour OM, et al. Among authors: naguib fn. Cancer Chemother Pharmacol. 2000;45(5):351-61. doi: 10.1007/s002800051002. Cancer Chemother Pharmacol. 2000. PMID: 10803917

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