Janson CA - Search Results

1

Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.

Qiu X, Janson CA, Smith WW, Green SM, McDevitt P, Johanson K, Carter P, Hibbs M, Lewis C, Chalker A, Fosberry A, Lalonde J, Berge J, Brown P, Houge-Frydrych CS, Jarvest RL. Qiu X, et al. Among authors: janson ca. Protein Sci. 2001 Oct;10(10):2008-16. doi: 10.1110/ps.18001. Protein Sci. 2001. PMID: 11567092 Free PMC article.

2

Crystal structure and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus.

Qiu X, Choudhry AE, Janson CA, Grooms M, Daines RA, Lonsdale JT, Khandekar SS. Qiu X, et al. Among authors: janson ca. Protein Sci. 2005 Aug;14(8):2087-94. doi: 10.1110/ps.051501605. Epub 2005 Jun 29. Protein Sci. 2005. PMID: 15987898 Free PMC article.

3

Interaction of tyrosyl aryl dipeptides with S. aureus tyrosyl tRNA synthetase: inhibition and crystal structure of a complex.

Jarvest RL, Berge JM, Houge-Frydrych CS, Janson C, Mensah LM, O'Hanlon PJ, Pope A, Saldanha A, Qiu X. Jarvest RL, et al. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2859-62. doi: 10.1016/s0960-894x(99)00488-6. Bioorg Med Chem Lett. 1999. PMID: 10522706

4

Structure of apo acyl carrier protein and a proposal to engineer protein crystallization through metal ions.

Qiu X, Janson CA. Qiu X, et al. Among authors: janson ca. Acta Crystallogr D Biol Crystallogr. 2004 Sep;60(Pt 9):1545-54. doi: 10.1107/S0907444904015422. Epub 2004 Aug 26. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15333924

5

Crystal structure of varicella-zoster virus protease.

Qiu X, Janson CA, Culp JS, Richardson SB, Debouck C, Smith WW, Abdel-Meguid SS. Qiu X, et al. Among authors: janson ca. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2874-9. doi: 10.1073/pnas.94.7.2874. Proc Natl Acad Sci U S A. 1997. PMID: 9096314 Free PMC article.

6

The crystal structure of human procathepsin K.

LaLonde JM, Zhao B, Janson CA, D'Alessio KJ, McQueney MS, Orsini MJ, Debouck CM, Smith WW. LaLonde JM, et al. Among authors: janson ca. Biochemistry. 1999 Jan 19;38(3):862-9. doi: 10.1021/bi9822271. Biochemistry. 1999. PMID: 9893980

7

Cooperative structural dynamics and a novel fidelity mechanism in histidyl-tRNA synthetases.

Qiu X, Janson CA, Blackburn MN, Chhohan IK, Hibbs M, Abdel-Meguid SS. Qiu X, et al. Among authors: janson ca. Biochemistry. 1999 Sep 21;38(38):12296-304. doi: 10.1021/bi990482v. Biochemistry. 1999. PMID: 10493797

8

Molecular basis for triclosan activity involves a flipping loop in the active site.

Qiu X, Janson CA, Court RI, Smyth MG, Payne DJ, Abdel-Meguid SS. Qiu X, et al. Among authors: janson ca. Protein Sci. 1999 Nov;8(11):2529-32. doi: 10.1110/ps.8.11.2529. Protein Sci. 1999. PMID: 10595560 Free PMC article.

9

Refined structures of beta-ketoacyl-acyl carrier protein synthase III.

Qiu X, Janson CA, Smith WW, Head M, Lonsdale J, Konstantinidis AK. Qiu X, et al. Among authors: janson ca. J Mol Biol. 2001 Mar 16;307(1):341-56. doi: 10.1006/jmbi.2000.4457. J Mol Biol. 2001. PMID: 11243824

10

Unique fold and active site in cytomegalovirus protease.

Qiu X, Culp JS, DiLella AG, Hellmig B, Hoog SS, Janson CA, Smith WW, Abdel-Meguid SS. Qiu X, et al. Among authors: janson ca. Nature. 1996 Sep 19;383(6597):275-9. doi: 10.1038/383275a0. Nature. 1996. PMID: 8805707

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