Moore JT - Search Results

1

Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism.

Willson TM, Jones SA, Moore JT, Kliewer SA. Willson TM, et al. Among authors: moore jt. Med Res Rev. 2001 Nov;21(6):513-22. doi: 10.1002/med.1023. Med Res Rev. 2001. PMID: 11607932 Review.

2

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.

Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT. Moore LB, et al. Among authors: moore jt. Mol Endocrinol. 2002 May;16(5):977-86. doi: 10.1210/mend.16.5.0828. Mol Endocrinol. 2002. PMID: 11981033

3

Genomics versus orphan nuclear receptors--a half-time report.

Willson TM, Moore JT. Willson TM, et al. Among authors: moore jt. Mol Endocrinol. 2002 Jun;16(6):1135-44. doi: 10.1210/mend.16.6.0849. Mol Endocrinol. 2002. PMID: 12040002 Review.

4

Nuclear receptor regulation of genes involved in bile acid metabolism.

Moore JT, Goodwin B, Willson TM, Kliewer SA. Moore JT, et al. Crit Rev Eukaryot Gene Expr. 2002;12(2):119-35. doi: 10.1615/critreveukaryotgeneexpr.v12.i2.30. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12434926 Review.

5

Functional and structural comparison of PXR and CAR.

Moore JT, Moore LB, Maglich JM, Kliewer SA. Moore JT, et al. Among authors: moore lb. Biochim Biophys Acta. 2003 Feb 17;1619(3):235-8. doi: 10.1016/s0304-4165(02)00481-6. Biochim Biophys Acta. 2003. PMID: 12573482 Review.

6

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. Among authors: moore lb, moore jt. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900 Free article.

7

Beyond the human genome: examples of nuclear receptor analysis in model organisms and potential for drug discovery.

Maglich JM, Sluder AE, Willson TM, Moore JT. Maglich JM, et al. Among authors: moore jt. Am J Pharmacogenomics. 2003;3(5):345-53. doi: 10.2165/00129785-200303050-00005. Am J Pharmacogenomics. 2003. PMID: 14575522 Review.

8

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway.

Kliewer SA, Moore JT, Wade L, Staudinger JL, Watson MA, Jones SA, McKee DD, Oliver BB, Willson TM, Zetterström RH, Perlmann T, Lehmann JM. Kliewer SA, et al. Among authors: moore jt. Cell. 1998 Jan 9;92(1):73-82. doi: 10.1016/s0092-8674(00)80900-9. Cell. 1998. PMID: 9489701 Free article.

9

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, Kliewer SA. Lehmann JM, et al. Among authors: moore jt. J Clin Invest. 1998 Sep 1;102(5):1016-23. doi: 10.1172/JCI3703. J Clin Invest. 1998. PMID: 9727070 Free PMC article.

10

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors.

Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Xu HE, et al. Among authors: moore lb, moore jt. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. doi: 10.1073/pnas.241410198. Epub 2001 Nov 6. Proc Natl Acad Sci U S A. 2001. PMID: 11698662 Free PMC article.

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