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Mobilized bone marrow cells repair the infarcted heart, improving function and survival.
Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Orlic D, et al. Among authors: limana f. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10344-9. doi: 10.1073/pnas.181177898. Epub 2001 Aug 14. Proc Natl Acad Sci U S A. 2001. PMID: 11504914 Free PMC article.
bcl-2 overexpression promotes myocyte proliferation.
Limana F, Urbanek K, Chimenti S, Quaini F, Leri A, Kajstura J, Nadal-Ginard B, Izumo S, Anversa P. Limana F, et al. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6257-62. doi: 10.1073/pnas.092672899. Proc Natl Acad Sci U S A. 2002. PMID: 11983915 Free PMC article.
Adult cardiac stem cells are multipotent and support myocardial regeneration.
Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal-Ginard B, Anversa P. Beltrami AP, et al. Among authors: limana f. Cell. 2003 Sep 19;114(6):763-76. doi: 10.1016/s0092-8674(03)00687-1. Cell. 2003. PMID: 14505575 Free article.
Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival.
Urbanek K, Rota M, Cascapera S, Bearzi C, Nascimbene A, De Angelis A, Hosoda T, Chimenti S, Baker M, Limana F, Nurzynska D, Torella D, Rotatori F, Rastaldo R, Musso E, Quaini F, Leri A, Kajstura J, Anversa P. Urbanek K, et al. Among authors: limana f. Circ Res. 2005 Sep 30;97(7):663-73. doi: 10.1161/01.RES.0000183733.53101.11. Epub 2005 Sep 1. Circ Res. 2005. PMID: 16141414
Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation.
Limana F, Germani A, Zacheo A, Kajstura J, Di Carlo A, Borsellino G, Leoni O, Palumbo R, Battistini L, Rastaldo R, Müller S, Pompilio G, Anversa P, Bianchi ME, Capogrossi MC. Limana F, et al. Circ Res. 2005 Oct 14;97(8):e73-83. doi: 10.1161/01.RES.0000186276.06104.04. Epub 2005 Sep 15. Circ Res. 2005. PMID: 16166556
41 results