Lefkowitz RJ - Search Results

1

Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice.

Kohout TA, Takaoka H, McDonald PH, Perry SJ, Mao L, Lefkowitz RJ, Rockman HA. Kohout TA, et al. Among authors: lefkowitz rj. Circulation. 2001 Nov 13;104(20):2485-91. doi: 10.1161/hc4501.098933. Circulation. 2001. PMID: 11705829

2

Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism.

Liggett SB, Ostrowski J, Chesnut LC, Kurose H, Raymond JR, Caron MG, Lefkowitz RJ. Liggett SB, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Mar 5;267(7):4740-6. J Biol Chem. 1992. PMID: 1311318 Free article.

3

Mutagenesis of the beta 2-adrenergic receptor: how structure elucidates function.

Ostrowski J, Kjelsberg MA, Caron MG, Lefkowitz RJ. Ostrowski J, et al. Among authors: lefkowitz rj. Annu Rev Pharmacol Toxicol. 1992;32:167-83. doi: 10.1146/annurev.pa.32.040192.001123. Annu Rev Pharmacol Toxicol. 1992. PMID: 1318669 Review. No abstract available.

4

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms.

Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Pitcher J, et al. Among authors: lefkowitz rj. Biochemistry. 1992 Mar 31;31(12):3193-7. doi: 10.1021/bi00127a021. Biochemistry. 1992. PMID: 1348186

5

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase.

Roth NS, Campbell PT, Caron MG, Lefkowitz RJ, Lohse MJ. Roth NS, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6201-4. doi: 10.1073/pnas.88.14.6201. Proc Natl Acad Sci U S A. 1991. PMID: 1648731 Free PMC article.

6

The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity.

Schwinn DA, Page SO, Middleton JP, Lorenz W, Liggett SB, Yamamoto K, Lapetina EG, Caron MG, Lefkowitz RJ, Cotecchia S. Schwinn DA, et al. Among authors: lefkowitz rj. Mol Pharmacol. 1991 Nov;40(5):619-26. Mol Pharmacol. 1991. PMID: 1658600

7

Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model.

Collins S, Lohse MJ, O'Dowd B, Caron MG, Lefkowitz RJ. Collins S, et al. Among authors: lefkowitz rj. Vitam Horm. 1991;46:1-39. doi: 10.1016/s0083-6729(08)60681-0. Vitam Horm. 1991. PMID: 1660639 Review. No abstract available.

8

Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein.

Fargin A, Yamamoto K, Cotecchia S, Goldsmith PK, Spiegel AM, Lapetina EG, Caron MG, Lefkowitz RJ. Fargin A, et al. Among authors: lefkowitz rj. Cell Signal. 1991;3(6):547-57. doi: 10.1016/0898-6568(91)90031-o. Cell Signal. 1991. PMID: 1786205

9

Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration.

Campbell PT, Hnatowich M, O'Dowd BF, Caron MG, Lefkowitz RJ, Hausdorff WP. Campbell PT, et al. Among authors: lefkowitz rj. Mol Pharmacol. 1991 Feb;39(2):192-8. Mol Pharmacol. 1991. PMID: 1847493

10

Coupling of a mutated form of the human beta 2-adrenergic receptor to Gi and Gs. Requirement for multiple cytoplasmic domains in the coupling process.

Liggett SB, Caron MG, Lefkowitz RJ, Hnatowich M. Liggett SB, et al. Among authors: lefkowitz rj. J Biol Chem. 1991 Mar 15;266(8):4816-21. J Biol Chem. 1991. PMID: 1848226 Free article.

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