Furneaux RH - Search Results

1

Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum.

Kicska GA, Tyler PC, Evans GB, Furneaux RH, Kim K, Schramm VL. Kicska GA, et al. Among authors: furneaux rh. J Biol Chem. 2002 Feb 1;277(5):3219-25. doi: 10.1074/jbc.M105905200. Epub 2001 Nov 13. J Biol Chem. 2002. PMID: 11707439 Free article.

2

Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase.

Kicska GA, Tyler PC, Evans GB, Furneaux RH, Schramm VL, Kim K. Kicska GA, et al. Among authors: furneaux rh. J Biol Chem. 2002 Feb 1;277(5):3226-31. doi: 10.1074/jbc.M105906200. Epub 2001 Nov 12. J Biol Chem. 2002. PMID: 11706018 Free article.

3

Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.

Kicska GA, Tyler PC, Evans GB, Furneaux RH, Shi W, Fedorov A, Lewandowicz A, Cahill SM, Almo SC, Schramm VL. Kicska GA, et al. Among authors: furneaux rh. Biochemistry. 2002 Dec 10;41(49):14489-98. doi: 10.1021/bi026636f. Biochemistry. 2002. PMID: 12463747

4

8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.

Evans GB, Furneaux RH, Gainsford GJ, Hanson JC, Kicska GA, Sauve AA, Schramm VL, Tyler PC. Evans GB, et al. Among authors: furneaux rh. J Med Chem. 2003 Jan 2;46(1):155-60. doi: 10.1021/jm0203332. J Med Chem. 2003. PMID: 12502369

5

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.

Sauve AA, Cahill SM, Zech SG, Basso LA, Lewandowicz A, Santos DS, Grubmeyer C, Evans GB, Furneaux RH, Tyler PC, McDermott A, Girvin ME, Schramm VL. Sauve AA, et al. Among authors: furneaux rh. Biochemistry. 2003 May 20;42(19):5694-705. doi: 10.1021/bi034003a. Biochemistry. 2003. PMID: 12741826

6

Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.

Lewandowicz A, Shi W, Evans GB, Tyler PC, Furneaux RH, Basso LA, Santos DS, Almo SC, Schramm VL. Lewandowicz A, et al. Among authors: furneaux rh. Biochemistry. 2003 May 27;42(20):6057-66. doi: 10.1021/bi0343830. Biochemistry. 2003. PMID: 12755607

7

Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase.

Lewandowicz A, Tyler PC, Evans GB, Furneaux RH, Schramm VL. Lewandowicz A, et al. Among authors: furneaux rh. J Biol Chem. 2003 Aug 22;278(34):31465-8. doi: 10.1074/jbc.C300259200. Epub 2003 Jul 3. J Biol Chem. 2003. PMID: 12842889 Free article.

8

Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.

Evans GB, Furneaux RH, Lewandowicz A, Schramm VL, Tyler PC. Evans GB, et al. Among authors: furneaux rh. J Med Chem. 2003 Jul 17;46(15):3412-23. doi: 10.1021/jm030145r. J Med Chem. 2003. PMID: 12852771

9

Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction.

Evans GB, Furneaux RH, Tyler PC, Schramm VL. Evans GB, et al. Among authors: furneaux rh. Org Lett. 2003 Oct 2;5(20):3639-40. doi: 10.1021/ol035293q. Org Lett. 2003. PMID: 14507192

10

Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.

Evans GB, Furneaux RH, Lewandowicz A, Schramm VL, Tyler PC. Evans GB, et al. Among authors: furneaux rh. J Med Chem. 2003 Nov 20;46(24):5271-6. doi: 10.1021/jm030305z. J Med Chem. 2003. PMID: 14613329

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