Loos WJ - Search Results

1

Dose and schedule-finding study of oral topotecan and weekly cisplatin in patients with recurrent ovarian cancer.

Gelderblom H, Sparreboom A, de Jonge MJ, Loos WJ, Wilms E, Mantel MA, Hennis B, Camlett I, Verweij J, van der Burg ME. Gelderblom H, et al. Among authors: loos wj. Br J Cancer. 2001 Oct 19;85(8):1124-9. doi: 10.1054/bjoc.2001.2014. Br J Cancer. 2001. PMID: 11710824 Free PMC article. Clinical Trial.

2

Phase I and pharmacokinetic study of XR11576, an oral topoisomerase I and II inhibitor, administered on days 1-5 of a 3-weekly cycle in patients with advanced solid tumours.

de Jonge MJ, Kaye S, Verweij J, Brock C, Reade S, Scurr M, van Doorn L, Verheij C, Loos W, Brindley C, Mistry P, Cooper M, Judson I. de Jonge MJ, et al. Br J Cancer. 2004 Oct 18;91(8):1459-65. doi: 10.1038/sj.bjc.6602178. Br J Cancer. 2004. PMID: 15452551 Free PMC article. Clinical Trial.

3

Docetaxel and paclitaxel inhibit DNA-adduct formation and intracellular accumulation of cisplatin in human leukocytes.

Ma J, Verweij J, Planting AS, Kolker HJ, Loos WJ, de Boer-Dennert M, van der Burg ME, Stoter G, Schellens JH. Ma J, et al. Among authors: loos wj. Cancer Chemother Pharmacol. 1996;37(4):382-4. doi: 10.1007/s002800050401. Cancer Chemother Pharmacol. 1996. PMID: 8548886 Free article.

4

Differential modulation of cisplatin accumulation in leukocytes and tumor cell lines by the paclitaxel vehicle Cremophor EL.

de Vos AI, Nooter K, Verweij J, Loos WJ, Brouwer E, de Bruijn P, Ruijgrok EJ, van der Burg ME, Stoter G, Sparreboom A. de Vos AI, et al. Among authors: loos wj. Ann Oncol. 1997 Nov;8(11):1145-50. doi: 10.1023/a:1008215720081. Ann Oncol. 1997. PMID: 9426335 Free article.

5

Oral topotecan given once or twice daily for ten days: a phase I pharmacology study in adult patients with solid tumors.

Gerrits CJ, Burris H, Schellens JH, Eckardt JR, Planting AS, van der Burg ME, Rodriguez GI, Loos WJ, van Beurden V, Hudson I, Fields S, Von Hoff DD, Verweij J. Gerrits CJ, et al. Among authors: loos wj. Clin Cancer Res. 1998 May;4(5):1153-8. Clin Cancer Res. 1998. PMID: 9607572 Clinical Trial.

6

Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line.

Ma J, Maliepaard M, Nooter K, Loos WJ, Kolker HJ, Verweij J, Stoter G, Schellens JH. Ma J, et al. Among authors: loos wj. Br J Cancer. 1998 May;77(10):1645-52. doi: 10.1038/bjc.1998.270. Br J Cancer. 1998. PMID: 9635842 Free PMC article.

7

Pharmacokinetics and bioavailability of oral 9-aminocamptothecin capsules in adult patients with solid tumors.

Sparreboom A, de Jonge MJ, Punt CJ, Nooter K, Loos WJ, Porro MG, Verweij J. Sparreboom A, et al. Among authors: loos wj. Clin Cancer Res. 1998 Aug;4(8):1915-9. Clin Cancer Res. 1998. PMID: 9717819 Clinical Trial.

8

Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo.

Sparreboom A, Verweij J, van der Burg ME, Loos WJ, Brouwer E, Viganò L, Locatelli A, de Vos AI, Nooter K, Stoter G, Gianni L. Sparreboom A, et al. Among authors: loos wj. Clin Cancer Res. 1998 Aug;4(8):1937-42. Clin Cancer Res. 1998. PMID: 9717822

9

A comparison of clinical pharmacodynamics of different administration schedules of oral topotecan (Hycamtin).

Gerrits CJ, Schellens JH, Burris H, Eckardt JR, Planting AS, van der Burg ME, Rodriguez GI, Loos WJ, van Beurden V, Hudson I, Von Hoff DD, Verweij J. Gerrits CJ, et al. Among authors: loos wj. Clin Cancer Res. 1999 Jan;5(1):69-75. Clin Cancer Res. 1999. PMID: 9918204 Clinical Trial.

10

Sparse-data set analysis for irinotecan and SN-38 pharmacokinetics in cancer patients co-treated with cisplatin.

Mathijssen RH, van Alphen RJ, de Jonge MJ, Verweij J, de Bruijn P, Loos WJ, Nooter K, Vernillet L, Stoter G, Sparreboom A. Mathijssen RH, et al. Among authors: loos wj. Anticancer Drugs. 1999 Jan;10(1):9-16. doi: 10.1097/00001813-199901000-00002. Anticancer Drugs. 1999. PMID: 10194542 Clinical Trial.

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