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A beta-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction.
Fiorucci S, Wallace JL, Mencarelli A, Distrutti E, Rizzo G, Farneti S, Morelli A, Tseng JL, Suramanyam B, Guilford WJ, Parkinson JF. Fiorucci S, et al. Among authors: mencarelli a. Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15736-41. doi: 10.1073/pnas.0404722101. Epub 2004 Oct 25. Proc Natl Acad Sci U S A. 2004. PMID: 15505205 Free PMC article.
NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension.
Fiorucci S, Antonelli E, Morelli O, Mencarelli A, Casini A, Mello T, Palazzetti B, Tallet D, del Soldato P, Morelli A. Fiorucci S, et al. Among authors: mencarelli a. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8897-902. doi: 10.1073/pnas.151136298. Epub 2001 Jul 10. Proc Natl Acad Sci U S A. 2001. PMID: 11447266 Free PMC article.
A NO-releasing derivative of acetaminophen spares the liver by acting at several checkpoints in the Fas pathway.
Fiorucci S, Antonelli E, Mencarelli A, Palazzetti B, Alvarez-Miller L, Muscara M, del Soldato P, Sanpaolo L, Wallace JL, Morelli A. Fiorucci S, et al. Among authors: mencarelli a. Br J Pharmacol. 2002 Feb;135(3):589-99. doi: 10.1038/sj.bjp.0704500. Br J Pharmacol. 2002. Retraction in: Br J Pharmacol. 2009 Mar;156(5):868. doi: 10.1111/j.1476-5381.2009.00272.x PMID: 11834606 Free PMC article. Retracted.
155 results