Lock RB - Search Results

1

MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cells.

Peaston AE, Gardaneh M, Franco AV, Hocker JE, Murphy KM, Farnsworth ML, Catchpoole DR, Haber M, Norris MD, Lock RB, Marshall GM. Peaston AE, et al. Among authors: lock rb. Br J Cancer. 2001 Nov 16;85(10):1564-71. doi: 10.1054/bjoc.2001.2144. Br J Cancer. 2001. PMID: 11720446 Free PMC article.

2

Dual modes of death induced by etoposide in human epithelial tumor cells allow Bcl-2 to inhibit apoptosis without affecting clonogenic survival.

Lock RB, Stribinskiene L. Lock RB, et al. Cancer Res. 1996 Sep 1;56(17):4006-12. Cancer Res. 1996. PMID: 8752171

3

Bcl-2 inhibits early apoptotic events and reveals post-mitotic multinucleation without affecting cell cycle arrest in human epithelial tumor cells exposed to etoposide.

Elliott MJ, Murphy KM, Stribinskiene L, Ranganathan V, Sturges E, Farnsworth ML, Lock RB. Elliott MJ, et al. Among authors: lock rb. Cancer Chemother Pharmacol. 1999;44(1):1-11. doi: 10.1007/s002800050938. Cancer Chemother Pharmacol. 1999. PMID: 10367743

4

Bax membrane insertion during Fas(CD95)-induced apoptosis precedes cytochrome c release and is inhibited by Bcl-2.

Murphy KM, Streips UN, Lock RB. Murphy KM, et al. Among authors: lock rb. Oncogene. 1999 Oct 28;18(44):5991-9. doi: 10.1038/sj.onc.1203001. Oncogene. 1999. PMID: 10557088

5

Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells.

Murphy KM, Ranganathan V, Farnsworth ML, Kavallaris M, Lock RB. Murphy KM, et al. Among authors: lock rb. Cell Death Differ. 2000 Jan;7(1):102-11. doi: 10.1038/sj.cdd.4400597. Cell Death Differ. 2000. PMID: 10713725

6

Bcl-2 inhibits a Fas-induced conformational change in the Bax N terminus and Bax mitochondrial translocation.

Murphy KM, Streips UN, Lock RB. Murphy KM, et al. Among authors: lock rb. J Biol Chem. 2000 Jun 9;275(23):17225-8. doi: 10.1074/jbc.C900590199. J Biol Chem. 2000. PMID: 10751382 Free article.

7

High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.

Catts VS, Farnsworth ML, Haber M, Norris MD, Lutze-Mann LH, Lock RB. Catts VS, et al. Among authors: lock rb. Leukemia. 2001 Jun;15(6):929-35. doi: 10.1038/sj.leu.2402128. Leukemia. 2001. PMID: 11417479

8

The potential tumour suppressor role for caspase-9 (CASP9) in the childhood malignancy, neuroblastoma.

Catchpoole DR, Lock RB. Catchpoole DR, et al. Among authors: lock rb. Eur J Cancer. 2001 Nov;37(17):2217-21. doi: 10.1016/s0959-8049(01)00273-8. Eur J Cancer. 2001. PMID: 11677110

9

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse.

Lock RB, Liem N, Farnsworth ML, Milross CG, Xue C, Tajbakhsh M, Haber M, Norris MD, Marshall GM, Rice AM. Lock RB, et al. Blood. 2002 Jun 1;99(11):4100-8. doi: 10.1182/blood.v99.11.4100. Blood. 2002. PMID: 12010813 Free article.

10

Testing of new agents in childhood cancer preclinical models: meeting summary.

Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K, Yu A, Yu J, Smith MA. Houghton PJ, et al. Among authors: lock rb. Clin Cancer Res. 2002 Dec;8(12):3646-57. Clin Cancer Res. 2002. PMID: 12473573

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