Uetrecht J - Search Results

1

Prediction of a new drug's potential to cause idiosyncratic reactions.

Uetrecht J. Uetrecht J. Curr Opin Drug Discov Devel. 2001 Jan;4(1):55-9. Curr Opin Drug Discov Devel. 2001. PMID: 11727323 Review.

2

The role of leukocyte-generated reactive metabolites in the pathogenesis of idiosyncratic drug reactions.

Uetrecht JP. Uetrecht JP. Drug Metab Rev. 1992;24(3):299-366. doi: 10.3109/03602539208996297. Drug Metab Rev. 1992. PMID: 1628536 Review.

3

Metabolism of drugs by activated leukocytes: implications for drug-induced lupus and other drug hypersensitivity reactions.

Uetrecht J. Uetrecht J. Adv Exp Med Biol. 1991;283:121-32. doi: 10.1007/978-1-4684-5877-0_13. Adv Exp Med Biol. 1991. PMID: 2068978 Review.

4

Idiosyncratic drug reactions: possible role of reactive metabolites generated by leukocytes.

Uetrecht JP. Uetrecht JP. Pharm Res. 1989 Apr;6(4):265-73. doi: 10.1023/a:1015934104984. Pharm Res. 1989. PMID: 2664753 Review.

5

Current trends in drug-induced autoimmunity.

Uetrecht JP. Uetrecht JP. Toxicology. 1997 Apr 11;119(1):37-43. doi: 10.1016/s0300-483x(96)03594-9. Toxicology. 1997. PMID: 9129193 Review.

6

New concepts in immunology relevant to idiosyncratic drug reactions: the "danger hypothesis" and innate immune system.

Uetrecht JP. Uetrecht JP. Chem Res Toxicol. 1999 May;12(5):387-95. doi: 10.1021/tx980249i. Chem Res Toxicol. 1999. PMID: 10328748 Review. No abstract available.

7

Idiosyncratic drug reactions: the reactive metabolite syndromes.

Knowles SR, Uetrecht J, Shear NH. Knowles SR, et al. Among authors: uetrecht j. Lancet. 2000 Nov 4;356(9241):1587-91. doi: 10.1016/S0140-6736(00)03137-8. Lancet. 2000. PMID: 11075787 Review.

8

Is it possible to more accurately predict which drug candidates will cause idiosyncratic drug reactions?

Uetrecht JP. Uetrecht JP. Curr Drug Metab. 2000 Sep;1(2):133-41. doi: 10.2174/1389200003339081. Curr Drug Metab. 2000. PMID: 11465079 Review.

9

Mechanism of idiosyncratic drug reactions: reactive metabolite formation, protein binding and the regulation of the immune system.

Ju C, Uetrecht JP. Ju C, et al. Among authors: uetrecht jp. Curr Drug Metab. 2002 Aug;3(4):367-77. doi: 10.2174/1389200023337333. Curr Drug Metab. 2002. PMID: 12093356 Review.

10

N-oxidation of drugs associated with idiosyncratic drug reactions.

Uetrecht J. Uetrecht J. Drug Metab Rev. 2002 Aug;34(3):651-65. doi: 10.1081/dmr-120005667. Drug Metab Rev. 2002. PMID: 12214672 Review.

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