Schumacher WA - Search Results

1

Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.

Das J, Kimball SD, Hall SE, Han WC, Iwanowicz E, Lin J, Moquin RV, Reid JA, Sack JS, Malley MF, Chang CY, Chong S, Wang-Iverson DB, Roberts DG, Seiler SM, Schumacher WA, Ogletree ML. Das J, et al. Among authors: schumacher wa. Bioorg Med Chem Lett. 2002 Jan 7;12(1):45-9. doi: 10.1016/s0960-894x(01)00667-9. Bioorg Med Chem Lett. 2002. PMID: 11738570

2

Antiplatelet activity of the long-acting thromboxane receptor antagonist BMS 180,291 in monkeys.

Schumacher WA, Steinbacher TE, Youssef S, Ogletree ML. Schumacher WA, et al. Prostaglandins. 1992 Nov;44(5):389-97. doi: 10.1016/0090-6980(92)90135-g. Prostaglandins. 1992. PMID: 1301074

3

Thrombin inhibition compared with other antithrombotic drugs in rats.

Schumacher WA, Heran CH, Steinbacher TE, Megill JR, Bird JE, Giancarli MR, Durham SK. Schumacher WA, et al. Thromb Res. 1992 Oct 15;68(2):157-66. doi: 10.1016/0049-3848(92)90031-5. Thromb Res. 1992. PMID: 1475778

4

Pharmacological characterization of potent, long-acting thromboxane receptor antagonists, SQ 33,261 and SQ 33,552.

Harris DN, Michel IM, Goldenberg HJ, Hartl KS, Allen GT, Steinbacher TE, Schumacher WA, Han WC, Hall SE, Floyd DM, et al. Harris DN, et al. Among authors: schumacher wa. J Pharmacol Exp Ther. 1992 Apr;261(1):131-7. J Pharmacol Exp Ther. 1992. PMID: 1532833

5

Activity of the short-acting thromboxane receptor antagonist, SQ 30,741, in thrombolytic and vasospastic models in monkeys.

Schumacher WA, Heran CL, Hartl KS, Ogletree ML. Schumacher WA, et al. J Pharmacol Exp Ther. 1990 May;253(2):841-6. J Pharmacol Exp Ther. 1990. PMID: 2140131

6

Role of thromboxane receptor activation in the bronchospastic response to endothelin.

Schumacher WA, Steinbacher TE, Allen GT, Ogletree ML. Schumacher WA, et al. Prostaglandins. 1990 Jul;40(1):71-9. doi: 10.1016/0090-6980(90)90057-3. Prostaglandins. 1990. PMID: 2143841

7

Protamine-induced pulmonary hypertension in heparinized monkeys and pigs is inhibited by the thromboxane receptor antagonist SQ 30,741.

Schumacher WA, Heran CL, Ogletree ML. Schumacher WA, et al. Eicosanoids. 1990;3(2):87-93. Eicosanoids. 1990. PMID: 2144979

8

Magnitude of thromboxane receptor antagonism necessary for antithrombotic activity in monkeys.

Schumacher WA, Heran CL, Goldenberg HJ, Harris DN, Ogletree ML. Schumacher WA, et al. Am J Physiol. 1989 Mar;256(3 Pt 2):H726-34. doi: 10.1152/ajpheart.1989.256.3.H726. Am J Physiol. 1989. PMID: 2522282

9

Role of thromboxane receptors in Forssman shock in guinea pigs.

Schumacher WA, Steinbacher TE, Allen GT, Ogletree ML. Schumacher WA, et al. J Appl Physiol (1985). 1989 Jul;67(1):44-51. doi: 10.1152/jappl.1989.67.1.44. J Appl Physiol (1985). 1989. PMID: 2527227

10

Leukotrienes cause mesenteric vasoconstriction and hemoconcentration in rats without activating thromboxane receptors.

Schumacher WA, Heran CL, Allen GT, Ogletree ML. Schumacher WA, et al. Prostaglandins. 1989 Sep;38(3):335-44. doi: 10.1016/0090-6980(89)90137-8. Prostaglandins. 1989. PMID: 2528783

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