Kay R - Search Results

1

The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation.

Tognon C, Garnett M, Kenward E, Kay R, Morrison K, Sorensen PH. Tognon C, et al. Among authors: kay r. Cancer Res. 2001 Dec 15;61(24):8909-16. Cancer Res. 2001. PMID: 11751416

2

Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C.

Whitehead I, Kirk H, Tognon C, Trigo-Gonzalez G, Kay R. Whitehead I, et al. Among authors: kay r. J Biol Chem. 1995 Aug 4;270(31):18388-95. doi: 10.1074/jbc.270.31.18388. J Biol Chem. 1995. PMID: 7629163 Free article.

3

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

Tognon CE, Kirk HE, Passmore LA, Whitehead IP, Der CJ, Kay RJ. Tognon CE, et al. Among authors: kay rj. Mol Cell Biol. 1998 Dec;18(12):6995-7008. doi: 10.1128/MCB.18.12.6995. Mol Cell Biol. 1998. PMID: 9819387 Free PMC article.

4

RasGRP1 sensitizes an immature B cell line to antigen receptor-induced apoptosis.

Guilbault B, Kay RJ. Guilbault B, et al. J Biol Chem. 2004 May 7;279(19):19523-30. doi: 10.1074/jbc.M314273200. Epub 2004 Feb 17. J Biol Chem. 2004. PMID: 14970203 Free article.

5

Phosphoinositide 3-kinase regulates plasma membrane targeting of the Ras-specific exchange factor RasGRP1.

Zahedi B, Goo HJ, Beaulieu N, Tazmini G, Kay RJ, Cornell RB. Zahedi B, et al. J Biol Chem. 2011 Apr 8;286(14):12712-23. doi: 10.1074/jbc.M110.189605. Epub 2011 Feb 1. J Biol Chem. 2011. PMID: 21285350 Free PMC article.

6

Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor.

Whitehead I, Kirk H, Kay R. Whitehead I, et al. Among authors: kay r. Oncogene. 1995 Feb 16;10(4):713-21. Oncogene. 1995. PMID: 7862449

7

Regulation of RasGRP1 by B cell antigen receptor requires cooperativity between three domains controlling translocation to the plasma membrane.

Beaulieu N, Zahedi B, Goulding RE, Tazmini G, Anthony KV, Omeis SL, de Jong DR, Kay RJ. Beaulieu N, et al. Among authors: kay rj. Mol Biol Cell. 2007 Aug;18(8):3156-68. doi: 10.1091/mbc.e06-10-0932. Epub 2007 Jun 13. Mol Biol Cell. 2007. PMID: 17567957 Free PMC article.

8

Expression cloning of oncogenes by retroviral transfer of cDNA libraries.

Whitehead I, Kirk H, Kay R. Whitehead I, et al. Among authors: kay r. Mol Cell Biol. 1995 Feb;15(2):704-10. doi: 10.1128/MCB.15.2.704. Mol Cell Biol. 1995. PMID: 7823939 Free PMC article.

9

Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors.

Whitehead IP, Khosravi-Far R, Kirk H, Trigo-Gonzalez G, Der CJ, Kay R. Whitehead IP, et al. Among authors: kay r. J Biol Chem. 1996 Aug 2;271(31):18643-50. doi: 10.1074/jbc.271.31.18643. J Biol Chem. 1996. PMID: 8702517 Free article.

10

Membrane localization of RasGRP1 is controlled by an EF-hand, and by the GEF domain.

Tazmini G, Beaulieu N, Woo A, Zahedi B, Goulding RE, Kay RJ. Tazmini G, et al. Biochim Biophys Acta. 2009 Mar;1793(3):447-61. doi: 10.1016/j.bbamcr.2008.12.019. Epub 2009 Jan 3. Biochim Biophys Acta. 2009. PMID: 19168098 Free article.

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