Südhof TC - Search Results

1

Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.

Fernandez I, Araç D, Ubach J, Gerber SH, Shin O, Gao Y, Anderson RG, Südhof TC, Rizo J. Fernandez I, et al. Among authors: sudhof tc. Neuron. 2001 Dec 20;32(6):1057-69. doi: 10.1016/s0896-6273(01)00548-7. Neuron. 2001. PMID: 11754837 Free article.

2

Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1.

Li L, Shin OH, Rhee JS, Araç D, Rah JC, Rizo J, Südhof T, Rosenmund C. Li L, et al. J Biol Chem. 2006 Jun 9;281(23):15845-52. doi: 10.1074/jbc.M600888200. Epub 2006 Apr 4. J Biol Chem. 2006. PMID: 16595652 Free article.

3

Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cells.

Shin OH, Rizo J, Südhof TC. Shin OH, et al. Among authors: sudhof tc. Nat Neurosci. 2002 Jul;5(7):649-56. doi: 10.1038/nn869. Nat Neurosci. 2002. PMID: 12055633

4

Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1.

Fernández-Chacón R, Shin OH, Königstorfer A, Matos MF, Meyer AC, Garcia J, Gerber SH, Rizo J, Südhof TC, Rosenmund C. Fernández-Chacón R, et al. Among authors: sudhof tc. J Neurosci. 2002 Oct 1;22(19):8438-46. doi: 10.1523/JNEUROSCI.22-19-08438.2002. J Neurosci. 2002. PMID: 12351718 Free PMC article.

5

Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions.

Shin OH, Rhee JS, Tang J, Sugita S, Rosenmund C, Südhof TC. Shin OH, et al. Among authors: sudhof tc. Neuron. 2003 Jan 9;37(1):99-108. doi: 10.1016/s0896-6273(02)01145-5. Neuron. 2003. PMID: 12526776 Free article.

6

A conformational switch in the Piccolo C2A domain regulated by alternative splicing.

Garcia J, Gerber SH, Sugita S, Südhof TC, Rizo J. Garcia J, et al. Among authors: sudhof tc. Nat Struct Mol Biol. 2004 Jan;11(1):45-53. doi: 10.1038/nsmb707. Epub 2003 Dec 29. Nat Struct Mol Biol. 2004. PMID: 14718922

7

Unexpected Ca2+-binding properties of synaptotagmin 9.

Shin OH, Maximov A, Lim BK, Rizo J, Südhof TC. Shin OH, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2554-9. doi: 10.1073/pnas.0308477100. Proc Natl Acad Sci U S A. 2004. PMID: 14983047 Free PMC article.

8

Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4.

Dai H, Shin OH, Machius M, Tomchick DR, Südhof TC, Rizo J. Dai H, et al. Among authors: sudhof tc. Nat Struct Mol Biol. 2004 Sep;11(9):844-9. doi: 10.1038/nsmb817. Epub 2004 Aug 15. Nat Struct Mol Biol. 2004. PMID: 15311271

9

Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids.

Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, Johnson AE, Chiu W, Südhof TC, Rizo J. Araç D, et al. Among authors: sudhof tc. Nat Struct Mol Biol. 2006 Mar;13(3):209-17. doi: 10.1038/nsmb1056. Epub 2006 Feb 19. Nat Struct Mol Biol. 2006. PMID: 16491093

10

Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release.

Shin OH, Xu J, Rizo J, Südhof TC. Shin OH, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16469-74. doi: 10.1073/pnas.0908798106. Epub 2009 Sep 4. Proc Natl Acad Sci U S A. 2009. PMID: 19805322 Free PMC article.

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