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Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia.
Dinchuk JE, Focht RJ, Kelley JA, Henderson NL, Zolotarjova NI, Wynn R, Neff NT, Link J, Huber RM, Burn TC, Rupar MJ, Cunningham MR, Selling BH, Ma J, Stern AA, Hollis GF, Stein RB, Friedman PA. Dinchuk JE, et al. Among authors: stern aa. J Biol Chem. 2002 Apr 12;277(15):12970-7. doi: 10.1074/jbc.M110389200. Epub 2001 Dec 31. J Biol Chem. 2002. PMID: 11773073 Free article.