Cox AD - Search Results

1

A distinct class of dominant negative Ras mutants: cytosolic GTP-bound Ras effector domain mutants that inhibit Ras signaling and transformation and enhance cell adhesion.

Fiordalisi JJ, Holly SP, Johnson RL 2nd, Parise LV, Cox AD. Fiordalisi JJ, et al. Among authors: cox ad. J Biol Chem. 2002 Mar 29;277(13):10813-23. doi: 10.1074/jbc.M107684200. Epub 2002 Jan 17. J Biol Chem. 2002. PMID: 11799108 Free article.

2

Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct.

Khosravi-Far R, Clark GJ, Abe K, Cox AD, McLain T, Lutz RJ, Sinensky M, Der CJ. Khosravi-Far R, et al. Among authors: cox ad. J Biol Chem. 1992 Dec 5;267(34):24363-8. J Biol Chem. 1992. PMID: 1332953 Free article.

3

R-Ras induces malignant, but not morphologic, transformation of NIH3T3 cells.

Cox AD, Brtva TR, Lowe DG, Der CJ. Cox AD, et al. Oncogene. 1994 Nov;9(11):3281-8. Oncogene. 1994. PMID: 7936652

4

Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.

Westwick JK, Cox AD, Der CJ, Cobb MH, Hibi M, Karin M, Brenner DA. Westwick JK, et al. Among authors: cox ad. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6030-4. doi: 10.1073/pnas.91.13.6030. Proc Natl Acad Sci U S A. 1994. PMID: 8016110 Free PMC article.

5

The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation.

Cox AD, Garcia AM, Westwick JK, Kowalczyk JJ, Lewis MD, Brenner DA, Der CJ. Cox AD, et al. J Biol Chem. 1994 Jul 29;269(30):19203-6. J Biol Chem. 1994. PMID: 8034681 Free article.

6

The carboxyl-terminal CXXX sequence of Gi alpha, but not Rab5 or Rab11, supports Ras processing and transforming activity.

Cox AD, Graham SM, Solski PA, Buss JE, Der CJ. Cox AD, et al. J Biol Chem. 1993 Jun 5;268(16):11548-52. J Biol Chem. 1993. PMID: 8505289 Free article.

7

Biological assays for Ras transformation.

Clark GJ, Cox AD, Graham SM, Der CJ. Clark GJ, et al. Among authors: cox ad. Methods Enzymol. 1995;255:395-412. doi: 10.1016/s0076-6879(95)55042-9. Methods Enzymol. 1995. PMID: 8524126

8

TC21 causes transformation by Raf-independent signaling pathways.

Graham SM, Vojtek AB, Huff SY, Cox AD, Clark GJ, Cooper JA, Der CJ. Graham SM, et al. Among authors: cox ad. Mol Cell Biol. 1996 Nov;16(11):6132-40. doi: 10.1128/MCB.16.11.6132. Mol Cell Biol. 1996. PMID: 8887643 Free PMC article.

9

R-Ras is regulated by activators and effectors distinct from those that control Ras function.

Huff SY, Quilliam LA, Cox AD, Der CJ. Huff SY, et al. Among authors: cox ad. Oncogene. 1997 Jan 16;14(2):133-43. doi: 10.1038/sj.onc.1200815. Oncogene. 1997. PMID: 9010215

10

Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.

Oldham SM, Cox AD, Reynolds ER, Sizemore NS, Coffey RJ Jr, Der CJ. Oldham SM, et al. Among authors: cox ad. Oncogene. 1998 May;16(20):2565-73. doi: 10.1038/sj.onc.1201784. Oncogene. 1998. PMID: 9632133

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