Casarosa P - Search Results

1

Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor ORF74 constitutively activates p44/p42 MAPK and Akt via G(i) and phospholipase C-dependent signaling pathways.

Smit MJ, Verzijl D, Casarosa P, Navis M, Timmerman H, Leurs R. Smit MJ, et al. Among authors: casarosa p. J Virol. 2002 Feb;76(4):1744-52. doi: 10.1128/jvi.76.4.1744-1752.2002. J Virol. 2002. PMID: 11799169 Free PMC article.

2

The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashion.

Gruijthuijsen YK, Casarosa P, Kaptein SJ, Broers JL, Leurs R, Bruggeman CA, Smit MJ, Vink C. Gruijthuijsen YK, et al. Among authors: casarosa p. J Virol. 2002 Feb;76(3):1328-38. doi: 10.1128/jvi.76.3.1328-1338.2002. J Virol. 2002. PMID: 11773407 Free PMC article.

3

Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor.

Casarosa P, Menge WM, Minisini R, Otto C, van Heteren J, Jongejan A, Timmerman H, Moepps B, Kirchhoff F, Mertens T, Smit MJ, Leurs R. Casarosa P, et al. J Biol Chem. 2003 Feb 14;278(7):5172-8. doi: 10.1074/jbc.M210033200. Epub 2002 Nov 26. J Biol Chem. 2003. PMID: 12456673 Free article.

4

Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes.

Casarosa P, Gruijthuijsen YK, Michel D, Beisser PS, Holl J, Fitzsimons CP, Verzijl D, Bruggeman CA, Mertens T, Leurs R, Vink C, Smit MJ. Casarosa P, et al. J Biol Chem. 2003 Dec 12;278(50):50010-23. doi: 10.1074/jbc.M306530200. Epub 2003 Sep 30. J Biol Chem. 2003. PMID: 14522997 Free article.

5

Constitutively active Gq/11-coupled receptors enable signaling by co-expressed G(i/o)-coupled receptors.

Bakker RA, Casarosa P, Timmerman H, Smit MJ, Leurs R. Bakker RA, et al. Among authors: casarosa p. J Biol Chem. 2004 Feb 13;279(7):5152-61. doi: 10.1074/jbc.M309200200. Epub 2003 Nov 10. J Biol Chem. 2004. PMID: 14610092 Free article.

6

CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor.

Casarosa P, Waldhoer M, LiWang PJ, Vischer HF, Kledal T, Timmerman H, Schwartz TW, Smit MJ, Leurs R. Casarosa P, et al. J Biol Chem. 2005 Feb 4;280(5):3275-85. doi: 10.1074/jbc.M407536200. Epub 2004 Nov 16. J Biol Chem. 2005. PMID: 15546882 Free article.

7

Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28.

Casarosa P, Bakker RA, Verzijl D, Navis M, Timmerman H, Leurs R, Smit MJ. Casarosa P, et al. J Biol Chem. 2001 Jan 12;276(2):1133-7. doi: 10.1074/jbc.M008965200. J Biol Chem. 2001. PMID: 11050102 Free article.

8

Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28.

Hulshof JW, Casarosa P, Menge WM, Kuusisto LM, van der Goot H, Smit MJ, de Esch IJ, Leurs R. Hulshof JW, et al. Among authors: casarosa p. J Med Chem. 2005 Oct 6;48(20):6461-71. doi: 10.1021/jm050418d. J Med Chem. 2005. PMID: 16190772

9

Virally encoded G protein-coupled receptors: targets for potentially innovative anti-viral drug development.

Smit MJ, Vink C, Verzijl D, Casarosa P, Bruggeman CA, Leurs R. Smit MJ, et al. Among authors: casarosa p. Curr Drug Targets. 2003 Jul;4(5):431-41. doi: 10.2174/1389450033491000. Curr Drug Targets. 2003. PMID: 12816350 Review.

10

The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis.

Waldhoer M, Casarosa P, Rosenkilde MM, Smit MJ, Leurs R, Whistler JL, Schwartz TW. Waldhoer M, et al. Among authors: casarosa p. J Biol Chem. 2003 May 23;278(21):19473-82. doi: 10.1074/jbc.M213179200. Epub 2003 Mar 18. J Biol Chem. 2003. PMID: 12646575 Free article.

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