Speiser D - Search Results

1

Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR.

Dutoit V, Rubio-Godoy V, Doucey MA, Batard P, Liénard D, Rimoldi D, Speiser D, Guillaume P, Cerottini JC, Romero P, Valmori D. Dutoit V, et al. Among authors: speiser d. J Immunol. 2002 Feb 1;168(3):1167-71. doi: 10.4049/jimmunol.168.3.1167. J Immunol. 2002. PMID: 11801651

2

Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection.

Speiser DE, Kyburz D, Stübi U, Hengartner H, Zinkernagel RM. Speiser DE, et al. J Immunol. 1992 Aug 1;149(3):972-80. J Immunol. 1992. PMID: 1634779

3

Viral peptide specific cytotoxic T lymphocytes are of high avidity to host-MHC but only low avidity to donor-MHC after allogeneic bone marrow transplantation.

Kyburz D, Speiser DE. Kyburz D, et al. Among authors: speiser de. Transpl Immunol. 1995 Jun;3(2):143-50. doi: 10.1016/0966-3274(95)80041-7. Transpl Immunol. 1995. PMID: 7582905

4

Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo.

Kyburz D, Speiser DE, Aebischer T, Hengartner H, Zinkernagel RM. Kyburz D, et al. Among authors: speiser de. J Immunol. 1993 Jun 1;150(11):5051-8. J Immunol. 1993. PMID: 7684417

5

T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides.

Kyburz D, Aichele P, Speiser DE, Hengartner H, Zinkernagel RM, Pircher H. Kyburz D, et al. Among authors: speiser de. Eur J Immunol. 1993 Aug;23(8):1956-62. doi: 10.1002/eji.1830230834. Eur J Immunol. 1993. PMID: 8344359

6

Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis.

Bachmann MF, Ohteki T, Faienza KM, Zakarian A, Kägi D, Speiser DE, Ohashi PS. Bachmann MF, et al. Among authors: speiser de. J Immunol. 1997 Nov 1;159(9):4165-70. J Immunol. 1997. PMID: 9379009

7

Normal responsiveness of CTLA-4-deficient anti-viral cytotoxic T cells.

Bachmann MF, Waterhouse P, Speiser DE, McKall-Faienza K, Mak TW, Ohashi PS. Bachmann MF, et al. Among authors: speiser de. J Immunol. 1998 Jan 1;160(1):95-100. J Immunol. 1998. PMID: 9551960

8

Inhibition of TCR triggering by a spectrum of altered peptide ligands suggests the mechanism for TCR antagonism.

Bachmann MF, Speiser DE, Zakarian A, Ohashi PS. Bachmann MF, et al. Among authors: speiser de. Eur J Immunol. 1998 Oct;28(10):3110-9. doi: 10.1002/(SICI)1521-4141(199810)28:10<3110::AID-IMMU3110>3.0.CO;2-5. Eur J Immunol. 1998. PMID: 9808179 Free article.

9

CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients.

Speiser DE, Valmori D, Rimoldi D, Pittet MJ, Liénard D, Cerundolo V, MacDonald HR, Cerottini JC, Romero P. Speiser DE, et al. Eur J Immunol. 1999 Jun;29(6):1990-9. doi: 10.1002/(SICI)1521-4141(199906)29:06<1990::AID-IMMU1990>3.0.CO;2-9. Eur J Immunol. 1999. PMID: 10382762 Free article.

10

Absence of co-stimulation and not the intensity of TCR signaling is critical for the induction of T cell unresponsiveness in vivo.

Bachmann MF, Speiser DE, Mak TW, Ohashi PS. Bachmann MF, et al. Among authors: speiser de. Eur J Immunol. 1999 Jul;29(7):2156-66. doi: 10.1002/(SICI)1521-4141(199907)29:07<2156::AID-IMMU2156>3.0.CO;2-P. Eur J Immunol. 1999. PMID: 10427978 Free article.

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