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Structure-based design and synthesis of a thyroid hormone receptor (TR) antagonist.
Baxter JD, Goede P, Apriletti JW, West BL, Feng W, Mellstrom K, Fletterick RJ, Wagner RL, Kushner PJ, Ribeiro RC, Webb P, Scanlan TS, Nilsson S. Baxter JD, et al. Among authors: fletterick rj. Endocrinology. 2002 Feb;143(2):517-24. doi: 10.1210/endo.143.2.8617. Endocrinology. 2002. PMID: 11796506
Two resistance to thyroid hormone mutants with impaired hormone binding.
Huber BR, Sandler B, West BL, Cunha Lima ST, Nguyen HT, Apriletti JW, Baxter JD, Fletterick RJ. Huber BR, et al. Among authors: fletterick rj. Mol Endocrinol. 2003 Apr;17(4):643-52. doi: 10.1210/me.2002-0095. Epub 2003 Jan 16. Mol Endocrinol. 2003. PMID: 12554782
Design of thyroid hormone receptor antagonists from first principles.
Webb P, Nguyen NH, Chiellini G, Yoshihara HA, Cunha Lima ST, Apriletti JW, Ribeiro RC, Marimuthu A, West BL, Goede P, Mellstrom K, Nilsson S, Kushner PJ, Fletterick RJ, Scanlan TS, Baxter JD. Webb P, et al. Among authors: fletterick rj. J Steroid Biochem Mol Biol. 2002 Dec;83(1-5):59-73. doi: 10.1016/s0960-0760(02)00270-4. J Steroid Biochem Mol Biol. 2002. PMID: 12650702 Review.
X-ray crystallographic and functional studies of thyroid hormone receptor.
Ribeiro RC, Apriletti JW, Wagner RL, Feng W, Kushner PJ, Nilsson S, Scanlan TS, West BL, Fletterick RJ, Baxter JD. Ribeiro RC, et al. Among authors: fletterick rj. J Steroid Biochem Mol Biol. 1998 Apr;65(1-6):133-41. doi: 10.1016/s0960-0760(98)00029-6. J Steroid Biochem Mol Biol. 1998. PMID: 9699866 Review.
Hormone selectivity in thyroid hormone receptors.
Wagner RL, Huber BR, Shiau AK, Kelly A, Cunha Lima ST, Scanlan TS, Apriletti JW, Baxter JD, West BL, Fletterick RJ. Wagner RL, et al. Among authors: fletterick rj. Mol Endocrinol. 2001 Mar;15(3):398-410. doi: 10.1210/mend.15.3.0608. Mol Endocrinol. 2001. PMID: 11222741
267 results