Gani D - Search Results

1

The 6-OH group of D-inositol 1-phosphate serves as an H-bond donor in the catalytic hydrolysis of the phosphate ester by inositol monophosphatase.

Miller DJ, Beaton MW, Wilkie J, Gani D. Miller DJ, et al. Among authors: gani d. Chembiochem. 2000 Nov 17;1(4):262-71. doi: 10.1002/1439-7633(20001117)1:4<262::AID-CBIC262>3.0.CO;2-%23. Chembiochem. 2000. PMID: 11828418

2

Preparation and properties of 6-substituted cyclohexane-1,2,4-triol derivatives: mechanistic probes for the inositol monophosphatase reaction.

Schulz J, Wilkie J, Beaton MW, Miller DJ, Gani D. Schulz J, et al. Among authors: gani d. Biochem Soc Trans. 1998 Aug;26(3):315-22. doi: 10.1042/bst0260315. Biochem Soc Trans. 1998. PMID: 9765871 Review. No abstract available.

3

Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity.

Miller DJ, Bashir-Uddin Surfraz M, Akhtar M, Gani D, Allemann RK. Miller DJ, et al. Among authors: gani d. Org Biomol Chem. 2004 Mar 7;2(5):671-88. doi: 10.1039/b312808c. Epub 2004 Feb 5. Org Biomol Chem. 2004. PMID: 14985807

4

NMR studies and semi-empirical energy calculations for cyclic ADP-ribose.

Rutherford TJ, Wilkie J, Vu CQ, Schnackerz KD, Jacobson MK, Gani D. Rutherford TJ, et al. Among authors: gani d. Nucleosides Nucleotides Nucleic Acids. 2001 Aug;20(8):1485-95. doi: 10.1081/NCN-100105243. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11554541

5

Chemical and kinetic mechanism of the inositol monophosphatase reaction and its inhibition by Li+.

Leech AP, Baker GR, Shute JK, Cohen MA, Gani D. Leech AP, et al. Among authors: gani d. Eur J Biochem. 1993 Mar 15;212(3):693-704. doi: 10.1111/j.1432-1033.1993.tb17707.x. Eur J Biochem. 1993. PMID: 8385008 Free article.

6

Protein phosphatase 1 catalyses the direct hydrolytic cleavage of phosphate monoester in a ternary complex mechanism.

Sanvoisin J, Gani D. Sanvoisin J, et al. Among authors: gani d. Bioorg Med Chem Lett. 2001 Feb 26;11(4):471-4. doi: 10.1016/s0960-894x(00)00694-6. Bioorg Med Chem Lett. 2001. PMID: 11229750

7

Structure-activity relationship on human serum paraoxonase (PON1) using substrate analogues and inhibitors.

Bargota RS, Akhtar M, Biggadike K, Gani D, Allemann RK. Bargota RS, et al. Among authors: gani d. Bioorg Med Chem Lett. 2003 May 19;13(10):1623-6. doi: 10.1016/s0960-894x(03)00290-7. Bioorg Med Chem Lett. 2003. PMID: 12729627

8

Lithium and myo-inositol homeostasis.

Gani D, Downes CP, Batty I, Bramham J. Gani D, et al. Biochim Biophys Acta. 1993 Jun 30;1177(3):253-69. doi: 10.1016/0167-4889(93)90121-5. Biochim Biophys Acta. 1993. PMID: 8391849 Review. No abstract available.

9

Mechanism of 3-methylaspartase probed using deuterium and solvent isotope effects and active-site directed reagents: identification of an essential cysteine residue.

Pollard JR, Richardson S, Akhtar M, Lasry P, Neal T, Botting NP, Gani D. Pollard JR, et al. Among authors: gani d. Bioorg Med Chem. 1999 May;7(5):949-75. doi: 10.1016/s0968-0896(99)00044-9. Bioorg Med Chem. 1999. PMID: 10400348

10

The purification and properties of myo-inositol monophosphatase from bovine brain.

Gee NS, Ragan CI, Watling KJ, Aspley S, Jackson RG, Reid GG, Gani D, Shute JK. Gee NS, et al. Among authors: gani d. Biochem J. 1988 Feb 1;249(3):883-9. doi: 10.1042/bj2490883. Biochem J. 1988. PMID: 2833231 Free PMC article.

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