Byrne B - Search Results

1

Transduction of human and mouse pancreatic islet cells using a bicistronic recombinant adeno-associated viral vector.

Kapturczak M, Zolotukhin S, Cross J, Pileggi A, Molano RD, Jorgensen M, Byrne B, Flotte TR, Ellis T, Inverardi L, Ricordi C, Nick H, Atkinson M, Agarwal A. Kapturczak M, et al. Among authors: byrne b. Mol Ther. 2002 Feb;5(2):154-60. doi: 10.1006/mthe.2002.0522. Mol Ther. 2002. PMID: 11829522 Free article.

2

Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap.

Conway JE, Zolotukhin S, Muzyczka N, Hayward GS, Byrne BJ. Conway JE, et al. Among authors: byrne bj. J Virol. 1997 Nov;71(11):8780-9. doi: 10.1128/JVI.71.11.8780-8789.1997. J Virol. 1997. PMID: 9343238 Free PMC article.

3

Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors.

Song S, Morgan M, Ellis T, Poirier A, Chesnut K, Wang J, Brantly M, Muzyczka N, Byrne BJ, Atkinson M, Flotte TR. Song S, et al. Among authors: byrne bj. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14384-8. doi: 10.1073/pnas.95.24.14384. Proc Natl Acad Sci U S A. 1998. PMID: 9826709 Free PMC article.

4

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield.

Zolotukhin S, Byrne BJ, Mason E, Zolotukhin I, Potter M, Chesnut K, Summerford C, Samulski RJ, Muzyczka N. Zolotukhin S, et al. Among authors: byrne bj. Gene Ther. 1999 Jun;6(6):973-85. doi: 10.1038/sj.gt.3300938. Gene Ther. 1999. PMID: 10455399

5

High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap.

Conway JE, Rhys CM, Zolotukhin I, Zolotukhin S, Muzyczka N, Hayward GS, Byrne BJ. Conway JE, et al. Among authors: byrne bj. Gene Ther. 1999 Jun;6(6):986-93. doi: 10.1038/sj.gt.3300937. Gene Ther. 1999. PMID: 10455400

6

CMV-beta-actin promoter directs higher expression from an adeno-associated viral vector in the liver than the cytomegalovirus or elongation factor 1 alpha promoter and results in therapeutic levels of human factor X in mice.

Xu L, Daly T, Gao C, Flotte TR, Song S, Byrne BJ, Sands MS, Parker Ponder K. Xu L, et al. Among authors: byrne bj. Hum Gene Ther. 2001 Mar 20;12(5):563-73. doi: 10.1089/104303401300042500. Hum Gene Ther. 2001. PMID: 11268288

7

Correction of the enzymatic and functional deficits in a model of Pompe disease using adeno-associated virus vectors.

Fraites TJ Jr, Schleissing MR, Shanely RA, Walter GA, Cloutier DA, Zolotukhin I, Pauly DF, Raben N, Plotz PH, Powers SK, Kessler PD, Byrne BJ. Fraites TJ Jr, et al. Mol Ther. 2002 May;5(5 Pt 1):571-8. doi: 10.1006/mthe.2002.0580. Mol Ther. 2002. PMID: 11991748 Free article.

8

Improved method of recombinant AAV2 delivery for systemic targeted gene therapy.

Mah C, Fraites TJ Jr, Zolotukhin I, Song S, Flotte TR, Dobson J, Batich C, Byrne BJ. Mah C, et al. Mol Ther. 2002 Jul;6(1):106-12. doi: 10.1006/mthe.2001.0636. Mol Ther. 2002. PMID: 12095310 Free article.

9

Virus-based gene delivery systems.

Mah C, Byrne BJ, Flotte TR. Mah C, et al. Clin Pharmacokinet. 2002;41(12):901-11. doi: 10.2165/00003088-200241120-00001. Clin Pharmacokinet. 2002. PMID: 12222993 Review.

10

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors.

Zolotukhin S, Potter M, Zolotukhin I, Sakai Y, Loiler S, Fraites TJ Jr, Chiodo VA, Phillipsberg T, Muzyczka N, Hauswirth WW, Flotte TR, Byrne BJ, Snyder RO. Zolotukhin S, et al. Methods. 2002 Oct;28(2):158-67. doi: 10.1016/s1046-2023(02)00220-7. Methods. 2002. PMID: 12413414

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