Takuwa Y - Search Results

1

Sphingosine-1-phosphate, a platelet-derived lysophospholipid mediator, negatively regulates cellular Rac activity and cell migration in vascular smooth muscle cells.

Ryu Y, Takuwa N, Sugimoto N, Sakurada S, Usui S, Okamoto H, Matsui O, Takuwa Y. Ryu Y, et al. Among authors: takuwa y, takuwa n. Circ Res. 2002 Feb 22;90(3):325-32. doi: 10.1161/hh0302.104455. Circ Res. 2002. PMID: 11861422

2

The Edg family G protein-coupled receptors for lysophospholipids: their signaling properties and biological activities.

Takuwa Y, Takuwa N, Sugimoto N. Takuwa Y, et al. Among authors: takuwa n. J Biochem. 2002 Jun;131(6):767-71. doi: 10.1093/oxfordjournals.jbchem.a003163. J Biochem. 2002. PMID: 12038970 Free article. Review.

3

Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform.

Sugimoto N, Takuwa N, Okamoto H, Sakurada S, Takuwa Y. Sugimoto N, et al. Among authors: takuwa y, takuwa n. Mol Cell Biol. 2003 Mar;23(5):1534-45. doi: 10.1128/MCB.23.5.1534-1545.2003. Mol Cell Biol. 2003. PMID: 12588974 Free PMC article.

4

Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity.

Arikawa K, Takuwa N, Yamaguchi H, Sugimoto N, Kitayama J, Nagawa H, Takehara K, Takuwa Y. Arikawa K, et al. Among authors: takuwa y, takuwa n. J Biol Chem. 2003 Aug 29;278(35):32841-51. doi: 10.1074/jbc.M305024200. Epub 2003 Jun 16. J Biol Chem. 2003. PMID: 12810709 Free article.

5

Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction.

Sakurada S, Takuwa N, Sugimoto N, Wang Y, Seto M, Sasaki Y, Takuwa Y. Sakurada S, et al. Among authors: takuwa y, takuwa n. Circ Res. 2003 Sep 19;93(6):548-56. doi: 10.1161/01.RES.0000090998.08629.60. Epub 2003 Aug 14. Circ Res. 2003. PMID: 12919947

6

[Molecular mechanisms of sphingosine-1-phosphate receptor S1P2/Edg5-mediated inhibition of Rac and cell migration].

Sugimoto N, Takuwa N, Takuwa Y. Sugimoto N, et al. Among authors: takuwa y, takuwa n. Seikagaku. 2003 Jul;75(7):597-600. Seikagaku. 2003. PMID: 12931651 Review. Japanese. No abstract available.

7

Blood lipid mediator sphingosine 1-phosphate potently stimulates platelet-derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5.

Usui S, Sugimoto N, Takuwa N, Sakagami S, Takata S, Kaneko S, Takuwa Y. Usui S, et al. Among authors: takuwa y, takuwa n. J Biol Chem. 2004 Mar 26;279(13):12300-11. doi: 10.1074/jbc.M305025200. Epub 2004 Jan 7. J Biol Chem. 2004. PMID: 14711826 Free article.

8

Inhibition of Rac activation as a mechanism for negative regulation of actin cytoskeletal reorganization and cell motility by cAMP.

Nagasawa SY, Takuwa N, Sugimoto N, Mabuchi H, Takuwa Y. Nagasawa SY, et al. Among authors: takuwa y, takuwa n. Biochem J. 2005 Feb 1;385(Pt 3):737-44. doi: 10.1042/BJ20041060. Biochem J. 2005. PMID: 15377280 Free PMC article.

9

Rho-dependent, Rho kinase-independent inhibitory regulation of Rac and cell migration by LPA1 receptor in Gi-inactivated CHO cells.

Sugimoto N, Takuwa N, Yoshioka K, Takuwa Y. Sugimoto N, et al. Among authors: takuwa y, takuwa n. Exp Cell Res. 2006 Jun 10;312(10):1899-908. doi: 10.1016/j.yexcr.2006.02.020. Epub 2006 Mar 27. Exp Cell Res. 2006. PMID: 16564043

10

The lysophospholipid mediator sphingosine-1-phosphate promotes angiogenesis in vivo in ischaemic hindlimbs of mice.

Oyama O, Sugimoto N, Qi X, Takuwa N, Mizugishi K, Koizumi J, Takuwa Y. Oyama O, et al. Among authors: takuwa y, takuwa n. Cardiovasc Res. 2008 May 1;78(2):301-7. doi: 10.1093/cvr/cvn002. Epub 2008 Jan 10. Cardiovasc Res. 2008. PMID: 18187460

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