Frew IJ - Search Results

1

The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice.

Dickins RA, Frew IJ, House CM, O'Bryan MK, Holloway AJ, Haviv I, Traficante N, de Kretser DM, Bowtell DD. Dickins RA, et al. Among authors: frew ij. Mol Cell Biol. 2002 Apr;22(7):2294-303. doi: 10.1128/MCB.22.7.2294-2303.2002. Mol Cell Biol. 2002. PMID: 11884614 Free PMC article.

2

Normal p53 function in primary cells deficient for Siah genes.

Frew IJ, Dickins RA, Cuddihy AR, Del Rosario M, Reinhard C, O'Connell MJ, Bowtell DD. Frew IJ, et al. Mol Cell Biol. 2002 Dec;22(23):8155-64. doi: 10.1128/MCB.22.23.8155-8164.2002. Mol Cell Biol. 2002. PMID: 12417719 Free PMC article.

3

A binding motif for Siah ubiquitin ligase.

House CM, Frew IJ, Huang HL, Wiche G, Traficante N, Nice E, Catimel B, Bowtell DD. House CM, et al. Among authors: frew ij. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3101-6. doi: 10.1073/pnas.0534783100. Epub 2003 Mar 7. Proc Natl Acad Sci U S A. 2003. PMID: 12626763 Free PMC article.

4

Generation and analysis of Siah2 mutant mice.

Frew IJ, Hammond VE, Dickins RA, Quinn JM, Walkley CR, Sims NA, Schnall R, Della NG, Holloway AJ, Digby MR, Janes PW, Tarlinton DM, Purton LE, Gillespie MT, Bowtell DD. Frew IJ, et al. Mol Cell Biol. 2003 Dec;23(24):9150-61. doi: 10.1128/MCB.23.24.9150-9161.2003. Mol Cell Biol. 2003. PMID: 14645526 Free PMC article.

5

Osteopenia in Siah1a mutant mice.

Frew IJ, Sims NA, Quinn JM, Walkley CR, Purton LE, Bowtell DD, Gillespie MT. Frew IJ, et al. J Biol Chem. 2004 Jul 9;279(28):29583-8. doi: 10.1074/jbc.M312755200. Epub 2004 May 3. J Biol Chem. 2004. PMID: 15123657 Free article.

6

Stress-induced decrease in TRAF2 stability is mediated by Siah2.

Habelhah H, Frew IJ, Laine A, Janes PW, Relaix F, Sassoon D, Bowtell DD, Ronai Z. Habelhah H, et al. Among authors: frew ij. EMBO J. 2002 Nov 1;21(21):5756-65. doi: 10.1093/emboj/cdf576. EMBO J. 2002. PMID: 12411493 Free PMC article.

7

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia.

Nakayama K, Frew IJ, Hagensen M, Skals M, Habelhah H, Bhoumik A, Kadoya T, Erdjument-Bromage H, Tempst P, Frappell PB, Bowtell DD, Ronai Z. Nakayama K, et al. Among authors: frew ij. Cell. 2004 Jun 25;117(7):941-52. doi: 10.1016/j.cell.2004.06.001. Cell. 2004. PMID: 15210114 Free article.

8

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

Frew IJ, Thoma CR, Georgiev S, Minola A, Hitz M, Montani M, Moch H, Krek W. Frew IJ, et al. EMBO J. 2008 Jun 18;27(12):1747-57. doi: 10.1038/emboj.2008.96. Epub 2008 May 22. EMBO J. 2008. PMID: 18497742 Free PMC article.

9

Genetic deletion of the long isoform of the von Hippel-Lindau tumour suppressor gene product alters microtubule dynamics.

Frew IJ, Smole Z, Thoma CR, Krek W. Frew IJ, et al. Eur J Cancer. 2013 Jul;49(10):2433-40. doi: 10.1016/j.ejca.2013.02.024. Epub 2013 Mar 27. Eur J Cancer. 2013. PMID: 23541568

10

VHL loss causes spindle misorientation and chromosome instability.

Thoma CR, Toso A, Gutbrodt KL, Reggi SP, Frew IJ, Schraml P, Hergovich A, Moch H, Meraldi P, Krek W. Thoma CR, et al. Among authors: frew ij. Nat Cell Biol. 2009 Aug;11(8):994-1001. doi: 10.1038/ncb1912. Epub 2009 Jul 20. Nat Cell Biol. 2009. PMID: 19620968

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