Brideau RJ - Search Results

1

Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses.

Brideau RJ, Knechtel ML, Huang A, Vaillancourt VA, Vera EE, Oien NL, Hopkins TA, Wieber JL, Wilkinson KF, Rush BD, Schwende FJ, Wathen MW. Brideau RJ, et al. Antiviral Res. 2002 Apr;54(1):19-28. doi: 10.1016/s0166-3542(01)00208-x. Antiviral Res. 2002. PMID: 11888654

2

Broad-spectrum antiherpes activities of 4-hydroxyquinoline carboxamides, a novel class of herpesvirus polymerase inhibitors.

Oien NL, Brideau RJ, Hopkins TA, Wieber JL, Knechtel ML, Shelly JA, Anstadt RA, Wells PA, Poorman RA, Huang A, Vaillancourt VA, Clayton TL, Tucker JA, Wathen MW. Oien NL, et al. Among authors: brideau rj. Antimicrob Agents Chemother. 2002 Mar;46(3):724-30. doi: 10.1128/AAC.46.3.724-730.2002. Antimicrob Agents Chemother. 2002. PMID: 11850254 Free PMC article.

3

Inhibition of clinical isolates of human cytomegalovirus and varicella zoster virus by PNU-183792, a 4-oxo-dihydroquinoline.

Knechtel ML, Huang A, Vaillancourt VA, Brideau RJ. Knechtel ML, et al. Among authors: brideau rj. J Med Virol. 2002 Oct;68(2):234-6. doi: 10.1002/jmv.10193. J Med Virol. 2002. PMID: 12210413

4

Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resistance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents.

Thomsen DR, Oien NL, Hopkins TA, Knechtel ML, Brideau RJ, Wathen MW, Homa FL. Thomsen DR, et al. Among authors: brideau rj. J Virol. 2003 Feb;77(3):1868-76. doi: 10.1128/jvi.77.3.1868-1876.2003. J Virol. 2003. PMID: 12525621 Free PMC article.

5

4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.

Schnute ME, Cudahy MM, Brideau RJ, Homa FL, Hopkins TA, Knechtel ML, Oien NL, Pitts TW, Poorman RA, Wathen MW, Wieber JL. Schnute ME, et al. Among authors: brideau rj. J Med Chem. 2005 Sep 8;48(18):5794-804. doi: 10.1021/jm050162b. J Med Chem. 2005. PMID: 16134946

6

Naphthalene carboxamides as inhibitors of human cytomegalovirus DNA polymerase.

Vaillancourt VA, Cudahy MM, Staley SA, Brideau RJ, Conrad SJ, Knechtel ML, Oien NL, Wieber JL, Yagi Y, Wathen MW. Vaillancourt VA, et al. Among authors: brideau rj. Bioorg Med Chem Lett. 2000 Sep 18;10(18):2079-81. doi: 10.1016/s0960-894x(00)00402-9. Bioorg Med Chem Lett. 2000. PMID: 10999475

7

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.

Schnute ME, Anderson DJ, Brideau RJ, Ciske FL, Collier SA, Cudahy MM, Eggen M, Genin MJ, Hopkins TA, Judge TM, Kim EJ, Knechtel ML, Nair SK, Nieman JA, Oien NL, Scott A, Tanis SP, Vaillancourt VA, Wathen MW, Wieber JL. Schnute ME, et al. Among authors: brideau rj. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3349-53. doi: 10.1016/j.bmcl.2007.03.102. Epub 2007 Apr 5. Bioorg Med Chem Lett. 2007. PMID: 17434304

8

7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.

Larsen SD, Zhang Z, DiPaolo BA, Manninen PR, Rohrer DC, Hageman MJ, Hopkins TA, Knechtel ML, Oien NL, Rush BD, Schwende FJ, Stefanski KJ, Wieber JL, Wilkinson KF, Zamora KM, Wathen MW, Brideau RJ. Larsen SD, et al. Among authors: brideau rj. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3840-4. doi: 10.1016/j.bmcl.2007.05.010. Epub 2007 May 10. Bioorg Med Chem Lett. 2007. PMID: 17513108

9

Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition.

Schnute ME, Brideau RJ, Collier SA, Cudahy MM, Hopkins TA, Knechtel ML, Oien NL, Sackett RS, Scott A, Stephan ML, Wathen MW, Wieber JL. Schnute ME, et al. Among authors: brideau rj. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3856-9. doi: 10.1016/j.bmcl.2008.06.060. Epub 2008 Jun 20. Bioorg Med Chem Lett. 2008. PMID: 18595689

10

A chimeric glycoprotein of human respiratory syncytial virus termed FG induces T-cell mediated immunity in mice.

Brideau RJ, Wathen MW. Brideau RJ, et al. Vaccine. 1991 Dec;9(12):863-4. doi: 10.1016/0264-410x(91)90003-o. Vaccine. 1991. PMID: 1811371

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