Wilkinson KF - Search Results

1

Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses.

Brideau RJ, Knechtel ML, Huang A, Vaillancourt VA, Vera EE, Oien NL, Hopkins TA, Wieber JL, Wilkinson KF, Rush BD, Schwende FJ, Wathen MW. Brideau RJ, et al. Among authors: wilkinson kf. Antiviral Res. 2002 Apr;54(1):19-28. doi: 10.1016/s0166-3542(01)00208-x. Antiviral Res. 2002. PMID: 11888654

2

7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.

Larsen SD, Zhang Z, DiPaolo BA, Manninen PR, Rohrer DC, Hageman MJ, Hopkins TA, Knechtel ML, Oien NL, Rush BD, Schwende FJ, Stefanski KJ, Wieber JL, Wilkinson KF, Zamora KM, Wathen MW, Brideau RJ. Larsen SD, et al. Among authors: wilkinson kf. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3840-4. doi: 10.1016/j.bmcl.2007.05.010. Epub 2007 May 10. Bioorg Med Chem Lett. 2007. PMID: 17513108

3

Development of a sensitive activity assay for high-volume evaluation of human renin inhibitory peptides in rat serum: results with U-71,038.

Ruwart MJ, Sharma SK, Harris DW, Lakings DB, Rush BD, Wilkinson KF, Cornette JC, Evans DB, Friis JM, Cook KJ, et al. Ruwart MJ, et al. Among authors: wilkinson kf. Pharm Res. 1990 Apr;7(4):407-10. doi: 10.1023/a:1015883709275. Pharm Res. 1990. PMID: 2194200

4

Peptides are better absorbed from the lung than the gut in the rat.

Hoover JL, Rush BD, Wilkinson KF, Day JS, Burton PS, Vidmar TJ, Ruwart MJ. Hoover JL, et al. Among authors: wilkinson kf. Pharm Res. 1992 Aug;9(8):1103-6. doi: 10.1023/a:1015879116950. Pharm Res. 1992. PMID: 1409386 No abstract available.

5

In vitro/in vivo models for peptide oral absorption: comparison of Caco-2 cell permeability with rat intestinal absorption of renin inhibitory peptides.

Conradi RA, Wilkinson KF, Rush BD, Hilgers AR, Ruwart MJ, Burton PS. Conradi RA, et al. Among authors: wilkinson kf. Pharm Res. 1993 Dec;10(12):1790-2. doi: 10.1023/a:1018990602102. Pharm Res. 1993. PMID: 8302767 No abstract available.

6

Desolvation energy: a major determinant of absorption, but not clearance, of peptides in rats.

Karls MS, Rush BD, Wilkinson KF, Vidmar TJ, Burton PS, Ruwart MJ. Karls MS, et al. Among authors: wilkinson kf. Pharm Res. 1991 Dec;8(12):1477-81. doi: 10.1023/a:1015882030289. Pharm Res. 1991. PMID: 1808609

7

Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors.

Islam I, Ng KY, Chong KT, McQuade TJ, Hui JO, Wilkinson KF, Rush BD, Ruwart MJ, Borchardt RT, Fisher JF. Islam I, et al. Among authors: wilkinson kf. J Med Chem. 1994 Jan 21;37(2):293-304. doi: 10.1021/jm00028a013. J Med Chem. 1994. PMID: 8295217

8

Peptidomimetic HIV protease inhibitors: phosphate prodrugs with improved biological activities.

Chong KT, Ruwart MJ, Hinshaw RR, Wilkinson KF, Rush BD, Yancey MF, Strohbach JW, Thaisrivongs S. Chong KT, et al. Among authors: wilkinson kf. J Med Chem. 1993 Aug 20;36(17):2575-7. doi: 10.1021/jm00069a018. J Med Chem. 1993. PMID: 8355256 No abstract available.

9

Development of activity assays for high-volume evaluation of human immunodeficiency virus (HIV) protease inhibitors in rat serum: results with ditekiren.

Wilkinson KF, Rush BD, Sharma SK, Evans DB, Ruwart MJ, Friis JM, Bohanon MJ, Tomich PK. Wilkinson KF, et al. Pharm Res. 1993 Apr;10(4):562-6. doi: 10.1023/a:1018950003185. Pharm Res. 1993. PMID: 8483839

10

Peptide to glycopeptide: glycosylated oligopeptide renin inhibitors with attenuated in vivo clearance properties.

Fisher JF, Harrison AW, Bundy GL, Wilkinson KF, Rush BD, Ruwart MJ. Fisher JF, et al. Among authors: wilkinson kf. J Med Chem. 1991 Oct;34(10):3140-3. doi: 10.1021/jm00114a026. J Med Chem. 1991. PMID: 1920364 No abstract available.

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