Coombes RC - Search Results

1

Histone deacetylase inhibitors in cancer treatment.

Vigushin DM, Coombes RC. Vigushin DM, et al. Among authors: coombes rc. Anticancer Drugs. 2002 Jan;13(1):1-13. doi: 10.1097/00001813-200201000-00001. Anticancer Drugs. 2002. PMID: 11914636 Review.

2

Identification and characterization of limonene metabolites in patients with advanced cancer by liquid chromatography/mass spectrometry.

Poon GK, Vigushin D, Griggs LJ, Rowlands MG, Coombes RC, Jarman M. Poon GK, et al. Among authors: coombes rc. Drug Metab Dispos. 1996 May;24(5):565-71. Drug Metab Dispos. 1996. PMID: 8723738 Clinical Trial.

3

Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer. Cancer Research Campaign Phase I/II Clinical Trials Committee.

Vigushin DM, Poon GK, Boddy A, English J, Halbert GW, Pagonis C, Jarman M, Coombes RC. Vigushin DM, et al. Among authors: coombes rc. Cancer Chemother Pharmacol. 1998;42(2):111-7. doi: 10.1007/s002800050793. Cancer Chemother Pharmacol. 1998. PMID: 9654110 Clinical Trial.

4

Two weekly vinorelbine: administration in patients who have received at least two prior chemotherapy regimes for advanced breast cancer.

Udom DI, Vigushin DM, Linardou H, Graham H, Palmieri C, Coombes RC. Udom DI, et al. Among authors: coombes rc. Eur J Cancer. 2000 Jan;36(2):177-82. doi: 10.1016/s0959-8049(99)00219-1. Eur J Cancer. 2000. PMID: 10741275

5

Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.

Vigushin DM, Ali S, Pace PE, Mirsaidi N, Ito K, Adcock I, Coombes RC. Vigushin DM, et al. Among authors: coombes rc. Clin Cancer Res. 2001 Apr;7(4):971-6. Clin Cancer Res. 2001. PMID: 11309348

6

Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase.

Marson CM, Rioja AS, Brooke G, Coombes RC, Vigushin DM. Marson CM, et al. Among authors: coombes rc. Bioorg Med Chem Lett. 2002 Jan 21;12(2):255-9. doi: 10.1016/s0960-894x(01)00718-1. Bioorg Med Chem Lett. 2002. PMID: 11755366

7

Tamoxifen-related porphyria cutanea tarda.

Agarwal R, Peters TJ, Coombes RC, Vigushin DM. Agarwal R, et al. Among authors: coombes rc. Med Oncol. 2002;19(2):121-3. doi: 10.1385/MO:19:2:121. Med Oncol. 2002. PMID: 12180481

8

Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I.

Vigushin DM, Brooke G, Willows D, Coombes RC, Moody CJ. Vigushin DM, et al. Among authors: coombes rc. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3661-3. doi: 10.1016/j.bmcl.2003.08.022. Bioorg Med Chem Lett. 2003. PMID: 14552752

9

Aromatase inhibitors as adjuvant therapies in patients with breast cancer.

Coombes RC, Gibson L, Hall E, Emson M, Bliss J. Coombes RC, et al. J Steroid Biochem Mol Biol. 2003 Sep;86(3-5):309-11. doi: 10.1016/s0960-0760(03)00372-8. J Steroid Biochem Mol Biol. 2003. PMID: 14623526 Review.

10

Targeted histone deacetylase inhibition for cancer therapy.

Vigushin DM, Coombes RC. Vigushin DM, et al. Among authors: coombes rc. Curr Cancer Drug Targets. 2004 Mar;4(2):205-18. doi: 10.2174/1568009043481560. Curr Cancer Drug Targets. 2004. PMID: 15032670 Review.

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