Tobe K - Search Results

1

Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p.

Mori Y, Otabe S, Dina C, Yasuda K, Populaire C, Lecoeur C, Vatin V, Durand E, Hara K, Okada T, Tobe K, Boutin P, Kadowaki T, Froguel P. Mori Y, et al. Among authors: tobe k. Diabetes. 2002 Apr;51(4):1247-55. doi: 10.2337/diabetes.51.4.1247. Diabetes. 2002. PMID: 11916952

2

Sequential activation of MAP kinase activator, MAP kinases, and S6 peptide kinase in intact rat liver following insulin injection.

Tobe K, Kadowaki T, Hara K, Gotoh Y, Kosako H, Matsuda S, Tamemoto H, Ueki K, Akanuma Y, Nishida E, et al. Tobe K, et al. J Biol Chem. 1992 Oct 15;267(29):21089-97. J Biol Chem. 1992. PMID: 1328222 Free article.

3

Insulin and 12-O-tetradecanoylphorbol-13-acetate activation of two immunologically distinct myelin basic protein/microtubule-associated protein 2 (MBP/MAP2) kinases via de novo phosphorylation of threonine and tyrosine residues.

Tobe K, Kadowaki T, Tamemoto H, Ueki K, Hara K, Koshio O, Momomura K, Gotoh Y, Nishida E, Akanuma Y, et al. Tobe K, et al. J Biol Chem. 1991 Dec 25;266(36):24793-803. J Biol Chem. 1991. PMID: 1662217 Free article.

4

Activation of MAP kinase and enhanced phosphorylation of the 350-kDa protein by mitogenic stimuli in quiescent Balb/c 3T3 cells.

Kawakami M, Nishida E, Tobe K, Hoshi M, Kadowaki T, Kasuga M, Sakai H. Kawakami M, et al. Among authors: tobe k. Exp Cell Res. 1991 Mar;193(1):120-6. doi: 10.1016/0014-4827(91)90545-6. Exp Cell Res. 1991. PMID: 1847329

5

Substrates for insulin-receptor kinase.

Kasuga M, Izumi T, Tobe K, Shiba T, Momomura K, Tashiro-Hashimoto Y, Kadowaki T. Kasuga M, et al. Among authors: tobe k. Diabetes Care. 1990 Mar;13(3):317-26. doi: 10.2337/diacare.13.3.317. Diabetes Care. 1990. PMID: 2155095 Review.

6

Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor.

Odawara M, Kadowaki T, Yamamoto R, Shibasaki Y, Tobe K, Accili D, Bevins C, Mikami Y, Matsuura N, Akanuma Y, et al. Odawara M, et al. Among authors: tobe k. Science. 1989 Jul 7;245(4913):66-8. doi: 10.1126/science.2544998. Science. 1989. PMID: 2544998

7

Stimulation of the phosphorylation of cytoskeletal 350-kDa and 300-kDa proteins by insulin-like growth factor-I, platelet-derived growth factor and phorbol ester in rat 3Y1 cells.

Nishida E, Tobe K, Kadowaki T, Kasuga M, Sato C, Sakai H. Nishida E, et al. Among authors: tobe k. Cell Struct Funct. 1988 Oct;13(5):417-23. doi: 10.1247/csf.13.417. Cell Struct Funct. 1988. PMID: 3224382 Free article.

8

Alteration in growth, cell morphology, and cytoskeletal structures of KB cells induced by epidermal growth factor and transforming growth factor-beta.

Koyasu S, Kadowaki T, Nishida E, Tobe K, Abe E, Kasuga M, Sakai H, Yahara I. Koyasu S, et al. Among authors: tobe k. Exp Cell Res. 1988 May;176(1):107-16. doi: 10.1016/0014-4827(88)90125-5. Exp Cell Res. 1988. PMID: 3259510

9

Identification of a 190-kDa protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1.

Tobe K, Tamemoto H, Yamauchi T, Aizawa S, Yazaki Y, Kadowaki T. Tobe K, et al. J Biol Chem. 1995 Mar 17;270(11):5698-701. doi: 10.1074/jbc.270.11.5698. J Biol Chem. 1995. PMID: 7534300 Free article.

Recently, we generated mice with a targeted disruption of the insulin receptor substrate-1 (IRS-1) gene and demonstrated that they exhibited growth retardation and mild insulin resistance, suggesting the presence of IRS-1-independent pathway that partially substitutes for IRS-1 i …

Recently, we generated mice with a targeted disruption of the insulin receptor substrate-1 (IRS-1) gene and demonstrated that they exhibited …

10

Protein kinase cascade activated by mechanical stress in cardiocytes: possible involvement of angiotensin II.

Komuro I, Yamazaki T, Katoh Y, Tobe K, Kadowaki T, Nagai R, Yazaki Y. Komuro I, et al. Among authors: tobe k. Eur Heart J. 1995 May;16 Suppl C:8-11. doi: 10.1093/eurheartj/16.suppl_c.8. Eur Heart J. 1995. PMID: 7556278

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