Nakajima M - Search Results

1

Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.

Yamazaki H, Nakamura M, Komatsu T, Ohyama K, Hatanaka N, Asahi S, Shimada N, Guengerich FP, Shimada T, Nakajima M, Yokoi T. Yamazaki H, et al. Among authors: nakajima m. Protein Expr Purif. 2002 Apr;24(3):329-37. doi: 10.1006/prep.2001.1578. Protein Expr Purif. 2002. PMID: 11922748

2

Formation of a novel quinone epoxide metabolite of troglitazone with cytotoxicity to HepG2 cells.

Yamamoto Y, Yamazaki H, Ikeda T, Watanabe T, Iwabuchi H, Nakajima M, Yokoi T. Yamamoto Y, et al. Among authors: nakajima m. Drug Metab Dispos. 2002 Feb;30(2):155-60. doi: 10.1124/dmd.30.2.155. Drug Metab Dispos. 2002. PMID: 11792684

3

High-performance liquid chromatographic assay for N-glucuronidation of nicotine and cotinine in human liver microsomes.

Nakajima M, Kwon JT, Tanaka E, Yokoi T. Nakajima M, et al. Anal Biochem. 2002 Mar 1;302(1):131-5. doi: 10.1006/abio.2001.5528. Anal Biochem. 2002. PMID: 11846386

4

Evaluation of approach to predict the contribution of multiple cytochrome P450s in drug metabolism using relative activity factor: effects of the differences in expression levels of NADPH-cytochrome P450 reductase and cytochrome b(5) in the expression system and the differences in the marker activities.

Nakajima M, Tane K, Nakamura S, Shimada N, Yamazaki H, Yokoi T. Nakajima M, et al. J Pharm Sci. 2002 Apr;91(4):952-63. doi: 10.1002/jps.10091. J Pharm Sci. 2002. PMID: 11948533

5

Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms.

Nakajima M, Tanaka E, Kobayashi T, Ohashi N, Kume T, Yokoi T. Nakajima M, et al. Drug Metab Dispos. 2002 Jun;30(6):636-42. doi: 10.1124/dmd.30.6.636. Drug Metab Dispos. 2002. PMID: 12019188

6

Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences.

Iwanari M, Nakajima M, Kizu R, Hayakawa K, Yokoi T. Iwanari M, et al. Among authors: nakajima m. Arch Toxicol. 2002 Jun;76(5-6):287-98. doi: 10.1007/s00204-002-0340-z. Epub 2002 Apr 10. Arch Toxicol. 2002. PMID: 12107646

7

Identification of catalase in human livers as a factor that enhances phenytoin dihydroxy metabolite formation by human liver microsomes.

Komatsu T, Yamazaki H, Nakajima M, Yokoi T. Komatsu T, et al. Among authors: nakajima m. Biochem Pharmacol. 2002 Jun 15;63(12):2081-90. doi: 10.1016/s0006-2952(02)01024-9. Biochem Pharmacol. 2002. PMID: 12110367

8

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis.

Nozawa T, Nakajima M, Tamai I, Noda K, Nezu J, Sai Y, Tsuji A, Yokoi T. Nozawa T, et al. Among authors: nakajima m. J Pharmacol Exp Ther. 2002 Aug;302(2):804-13. doi: 10.1124/jpet.302.2.804. J Pharmacol Exp Ther. 2002. PMID: 12130747

9

Genotoxic activation of benzophenone and its two metabolites by human cytochrome P450s in SOS/umu assay.

Takemoto K, Yamazaki H, Nakajima M, Yokoi T. Takemoto K, et al. Among authors: nakajima m. Mutat Res. 2002 Aug 26;519(1-2):199-204. doi: 10.1016/s1383-5718(02)00141-9. Mutat Res. 2002. PMID: 12160905

10

Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes.

Nakajima M, Sakata N, Ohashi N, Kume T, Yokoi T. Nakajima M, et al. Drug Metab Dispos. 2002 Nov;30(11):1250-6. doi: 10.1124/dmd.30.11.1250. Drug Metab Dispos. 2002. PMID: 12386132

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