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The Arf/p53 protein module, which induces apoptosis, down-regulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs.
Atsumi Y, Inase A, Osawa T, Sugihara E, Sakasai R, Fujimori H, Teraoka H, Saya H, Kanno M, Tashiro F, Nakagama H, Masutani M, Yoshioka K. Atsumi Y, et al. Among authors: kanno m. J Biol Chem. 2013 May 10;288(19):13269-77. doi: 10.1074/jbc.M112.402560. Epub 2013 Mar 27. J Biol Chem. 2013. PMID: 23536184 Free PMC article.
G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell.
Tahara E Jr, Tahara H, Kanno M, Naka K, Takeda Y, Matsuzaki T, Yamazaki R, Ishihara H, Yasui W, Barrett JC, Ide T, Tahara E. Tahara E Jr, et al. Among authors: kanno m. Cancer Immunol Immunother. 2005 Aug;54(8):729-40. doi: 10.1007/s00262-004-0645-2. Epub 2005 Feb 1. Cancer Immunol Immunother. 2005. PMID: 15685448 Free PMC article.
699 results