Al-Katib A - Search Results

1

Bcl-2 antisense oligonucleotides are effective against systemic but not central nervous system disease in severe combined immunodeficient mice bearing human t(14;18) follicular lymphoma.

Mohammad R, Abubakr Y, Dan M, Aboukameel A, Chow C, Mohamed A, Hamdy N, Al-Katib A. Mohammad R, et al. Clin Cancer Res. 2002 Apr;8(4):1277-83. Clin Cancer Res. 2002. PMID: 11948143

2

Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage.

Nabha SM, Mohammad RM, Dandashi MH, Coupaye-Gerard B, Aboukameel A, Pettit GR, Al-Katib AM. Nabha SM, et al. Clin Cancer Res. 2002 Aug;8(8):2735-41. Clin Cancer Res. 2002. PMID: 12171907

3

Preclinical evaluation of 2-[4-(7-chloro-2-quinoxalinyloxy)phenoxy]-propionic acid as a modulator of etoposide in human Waldenstrom's macroglobulinemia xenograft model.

Mensah-Osman EJ, Al-Katib AM, Mohammad RM. Mensah-Osman EJ, et al. Clin Cancer Res. 2003 Nov 15;9(15):5794-7. Clin Cancer Res. 2003. PMID: 14654565

4

Superior antitumor activity of SAR3419 to rituximab in xenograft models for non-Hodgkin's lymphoma.

Al-Katib AM, Aboukameel A, Mohammad R, Bissery MC, Zuany-Amorim C. Al-Katib AM, et al. Clin Cancer Res. 2009 Jun 15;15(12):4038-45. doi: 10.1158/1078-0432.CCR-08-2808. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509168

5

An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals.

Mohammad RM, Wu J, Azmi AS, Aboukameel A, Sosin A, Wu S, Yang D, Wang S, Al-Katib AM. Mohammad RM, et al. Mol Cancer. 2009 Dec 3;8:115. doi: 10.1186/1476-4598-8-115. Mol Cancer. 2009. PMID: 19958544 Free PMC article.

6

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma.

Mohammad RM, Wang S, Aboukameel A, Chen B, Wu X, Chen J, Al-Katib A. Mohammad RM, et al. Mol Cancer Ther. 2005 Jan;4(1):13-21. Mol Cancer Ther. 2005. PMID: 15657349

7

Preclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1.

Mohammad RM, Goustin AS, Aboukameel A, Chen B, Banerjee S, Wang G, Nikolovska-Coleska Z, Wang S, Al-Katib A. Mohammad RM, et al. Clin Cancer Res. 2007 Apr 1;13(7):2226-35. doi: 10.1158/1078-0432.CCR-06-1574. Clin Cancer Res. 2007. PMID: 17404107

8

Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model.

Arnold AA, Aboukameel A, Chen J, Yang D, Wang S, Al-Katib A, Mohammad RM. Arnold AA, et al. Mol Cancer. 2008 Feb 14;7:20. doi: 10.1186/1476-4598-7-20. Mol Cancer. 2008. PMID: 18275607 Free PMC article.

9

Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.

Sun Y, Wu J, Aboukameel A, Banerjee S, Arnold AA, Chen J, Nikolovska-Coleska Z, Lin Y, Ling X, Yang D, Wang S, Al-Katib A, Mohammad RM. Sun Y, et al. Cancer Biol Ther. 2008 Sep;7(9):1418-26. doi: 10.4161/cbt.7.9.6430. Epub 2008 Sep 4. Cancer Biol Ther. 2008. PMID: 18769131 Free PMC article.

10

I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma.

Al-Katib A, Arnold AA, Aboukameel A, Sosin A, Smith P, Mohamed AN, Beck FW, Mohammad RM. Al-Katib A, et al. Mol Cancer. 2010 Sep 1;9:228. doi: 10.1186/1476-4598-9-228. Mol Cancer. 2010. PMID: 20809973 Free PMC article.

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