Van Gennip AH - Search Results

1

Reduced 5-FU clearance in a patient with low DPD activity due to heterozygosity for a mutant allele of the DPYD gene.

Maring JG, van Kuilenburg AB, Haasjes J, Piersma H, Groen HJ, Uges DR, Van Gennip AH, De Vries EG. Maring JG, et al. Among authors: van gennip ah, van kuilenburg ab. Br J Cancer. 2002 Apr 8;86(7):1028-33. doi: 10.1038/sj.bjc.6600208. Br J Cancer. 2002. PMID: 11953843 Free PMC article.

2

Profound variation in dihydropyrimidine dehydrogenase activity in human blood cells: major implications for the detection of partly deficient patients.

Van Kuilenburg AB, van Lenthe H, Blom MJ, Mul EP, Van Gennip AH. Van Kuilenburg AB, et al. Among authors: van gennip ah, van lenthe h. Br J Cancer. 1999 Feb;79(3-4):620-6. doi: 10.1038/sj.bjc.6690097. Br J Cancer. 1999. PMID: 10027339 Free PMC article.

3

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene.

van Kuilenburg AB, Haasjes J, Richel DJ, Zoetekouw L, Van Lenthe H, De Abreu RA, Maring JG, Vreken P, van Gennip AH. van Kuilenburg AB, et al. Among authors: van gennip ah, van lenthe h. Clin Cancer Res. 2000 Dec;6(12):4705-12. Clin Cancer Res. 2000. PMID: 11156223

4

Dihydropyrimidinase deficiency and severe 5-fluorouracil toxicity.

van Kuilenburg AB, Meinsma R, Zonnenberg BA, Zoetekouw L, Baas F, Matsuda K, Tamaki N, van Gennip AH. van Kuilenburg AB, et al. Among authors: van gennip ah. Clin Cancer Res. 2003 Oct 1;9(12):4363-7. Clin Cancer Res. 2003. PMID: 14555507

5

Increased risk of grade IV neutropenia after administration of 5-fluorouracil due to a dihydropyrimidine dehydrogenase deficiency: high prevalence of the IVS14+1g>a mutation.

Van Kuilenburg AB, Meinsma R, Zoetekouw L, Van Gennip AH. Van Kuilenburg AB, et al. Among authors: van gennip ah. Int J Cancer. 2002 Sep 20;101(3):253-8. doi: 10.1002/ijc.10599. Int J Cancer. 2002. PMID: 12209976

6

Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency.

van Kuilenburg AB, De Abreu RA, van Gennip AH. van Kuilenburg AB, et al. Among authors: van gennip ah. Ann Clin Biochem. 2003 Jan;40(Pt 1):41-5. doi: 10.1258/000456303321016150. Ann Clin Biochem. 2003. PMID: 12542909 Review.

7

Dihydropyrimidine dehydrogenase (DPD) deficiency: identification and expression of missense mutations C29R, R886H and R235W.

Vreken P, Van Kuilenburg AB, Meinsma R, van Gennip AH. Vreken P, et al. Among authors: van gennip ah, van kuilenburg ab. Hum Genet. 1997 Dec;101(3):333-8. doi: 10.1007/s004390050637. Hum Genet. 1997. PMID: 9439663

8

Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency.

van Kuilenburg AB, Muller EW, Haasjes J, Meinsma R, Zoetekouw L, Waterham HR, Baas F, Richel DJ, van Gennip AH. van Kuilenburg AB, et al. Among authors: van gennip ah. Clin Cancer Res. 2001 May;7(5):1149-53. Clin Cancer Res. 2001. PMID: 11350878

9

Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls.

Raida M, Schwabe W, Häusler P, Van Kuilenburg AB, Van Gennip AH, Behnke D, Höffken K. Raida M, et al. Among authors: van gennip ah, van kuilenburg ab. Clin Cancer Res. 2001 Sep;7(9):2832-9. Clin Cancer Res. 2001. PMID: 11555601

10

Dihydropyrimidine dehydrogenase (DPD) deficiency: novel mutations in the DPD gene.

van Kuilenburg AB, Haasjes J, Meinsma R, Waterham HR, Vreken P, van Gennip AH. van Kuilenburg AB, et al. Among authors: van gennip ah. Adv Exp Med Biol. 2000;486:247-50. doi: 10.1007/0-306-46843-3_48. Adv Exp Med Biol. 2000. PMID: 11783493 No abstract available.

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