Christian EL - Search Results

1

Evidence for a polynuclear metal ion binding site in the catalytic domain of ribonuclease P RNA.

Christian EL, Kaye NM, Harris ME. Christian EL, et al. EMBO J. 2002 May 1;21(9):2253-62. doi: 10.1093/emboj/21.9.2253. EMBO J. 2002. PMID: 11980722 Free PMC article.

2

NAIM and site-specific functional group modification analysis of RNase P RNA: magnesium dependent structure within the conserved P1-P4 multihelix junction contributes to catalysis.

Kaye NM, Christian EL, Harris ME. Kaye NM, et al. Among authors: christian el. Biochemistry. 2002 Apr 9;41(14):4533-45. doi: 10.1021/bi012158h. Biochemistry. 2002. PMID: 11926814

3

Analysis of substrate recognition by the ribonucleoprotein endonuclease RNase P.

Christian EL, Zahler NH, Kaye NM, Harris ME. Christian EL, et al. Methods. 2002 Nov;28(3):307-22. doi: 10.1016/s1046-2023(02)00238-4. Methods. 2002. PMID: 12431435 Review.

4

Conservation of helical structure contributes to functional metal ion interactions in the catalytic domain of ribonuclease P RNA.

Kaye NM, Zahler NH, Christian EL, Harris ME. Kaye NM, et al. Among authors: christian el. J Mol Biol. 2002 Nov 29;324(3):429-42. doi: 10.1016/s0022-2836(02)01094-x. J Mol Biol. 2002. PMID: 12445779

5

Recognition of the 5' leader of pre-tRNA substrates by the active site of ribonuclease P.

Zahler NH, Christian EL, Harris ME. Zahler NH, et al. Among authors: christian el. RNA. 2003 Jun;9(6):734-45. doi: 10.1261/rna.5220703. RNA. 2003. PMID: 12756331 Free PMC article.

6

Recent insights into the structure and function of the ribonucleoprotein enzyme ribonuclease P.

Harris ME, Christian EL. Harris ME, et al. Among authors: christian el. Curr Opin Struct Biol. 2003 Jun;13(3):325-33. doi: 10.1016/s0959-440x(03)00069-1. Curr Opin Struct Biol. 2003. PMID: 12831883 Review.

7

The pre-tRNA nucleotide base and 2'-hydroxyl at N(-1) contribute to fidelity in tRNA processing by RNase P.

Zahler NH, Sun L, Christian EL, Harris ME. Zahler NH, et al. Among authors: christian el. J Mol Biol. 2005 Feb 4;345(5):969-85. doi: 10.1016/j.jmb.2004.10.080. Epub 2004 Dec 8. J Mol Biol. 2005. PMID: 15644198

8

The P4 metal binding site in RNase P RNA affects active site metal affinity through substrate positioning.

Christian EL, Smith KM, Perera N, Harris ME. Christian EL, et al. RNA. 2006 Aug;12(8):1463-7. doi: 10.1261/rna.158606. Epub 2006 Jul 5. RNA. 2006. PMID: 16822954 Free PMC article.

9

RNA crosslinking methods.

Harris ME, Christian EL. Harris ME, et al. Among authors: christian el. Methods Enzymol. 2009;468:127-46. doi: 10.1016/S0076-6879(09)68007-1. Methods Enzymol. 2009. PMID: 20946768 Free PMC article.

10

Identification of individual nucleotides in the bacterial ribonuclease P ribozyme adjacent to the pre-tRNA cleavage site by short-range photo-cross-linking.

Christian EL, McPheeters DS, Harris ME. Christian EL, et al. Biochemistry. 1998 Dec 15;37(50):17618-28. doi: 10.1021/bi982050a. Biochemistry. 1998. PMID: 9860878

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