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CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells.
Pistillo MP, Tazzari PL, Palmisano GL, Pierri I, Bolognesi A, Ferlito F, Capanni P, Polito L, Ratta M, Pileri S, Piccioli M, Basso G, Rissotto L, Conte R, Gobbi M, Stirpe F, Ferrara GB. Pistillo MP, et al. Blood. 2003 Jan 1;101(1):202-9. doi: 10.1182/blood-2002-06-1668. Epub 2002 Aug 15. Blood. 2003. PMID: 12393538 Free article.
Anti-CTLA-4 human scFv antibodies prevent T-cell activation in transplantation.
Pistillo MP, Tazzari PL, Stirpe F, Bolognesi A, Polito L, Capanni P, Pioli C, Gatta L, Ubaldi V, Doria G, Conte R, Ferrara GB. Pistillo MP, et al. Transplant Proc. 2001 Feb-Mar;33(1-2):285-7. doi: 10.1016/s0041-1345(00)02012-1. Transplant Proc. 2001. PMID: 11266822 No abstract available.
CTLA-4 expressed by chemoresistant, as well as untreated, myeloid leukaemia cells can be targeted with ligands to induce apoptosis.
Laurent S, Palmisano GL, Martelli AM, Kato T, Tazzari PL, Pierri I, Clavio M, Dozin B, Balbi G, Megna M, Morabito A, Lamparelli T, Bacigalupo A, Gobbi M, Pistillo MP. Laurent S, et al. Among authors: pistillo mp. Br J Haematol. 2007 Feb;136(4):597-608. doi: 10.1111/j.1365-2141.2006.06472.x. Br J Haematol. 2007. PMID: 17367412 Free article.
Immunotoxins containing recombinant anti-CTLA-4 single-chain fragment variable antibodies and saporin: in vitro results and in vivo effects in an acute rejection model.
Tazzari PL, Polito L, Bolognesi A, Pistillo MP, Capanni P, Palmisano GL, Lemoli RM, Curti A, Biancone L, Camussi G, Conte R, Ferrara GB, Stirpe F. Tazzari PL, et al. Among authors: pistillo mp. J Immunol. 2001 Oct 15;167(8):4222-9. doi: 10.4049/jimmunol.167.8.4222. J Immunol. 2001. PMID: 11591743
Expression of CTLA-4 in nonhuman primate lymphocytes and its use as a potential target for specific immunotoxin-mediated apoptosis: results of in vitro studies.
Palmisano GL, Tazzari PL, Cozzi E, Bolognesi A, Polito L, Seveso M, Ancona E, Ricci F, Conte R, Stirpe F, Ferrara GB, Pistillo MP. Palmisano GL, et al. Among authors: pistillo mp. Clin Exp Immunol. 2004 Feb;135(2):259-66. doi: 10.1111/j.1365-2249.2003.02382.x. Clin Exp Immunol. 2004. PMID: 14738454 Free PMC article.
Analysis of HLA-G expression in breast cancer tissues.
Palmisano GL, Pistillo MP, Fardin P, Capanni P, Nicolò G, Salvi S, Spina B, Pasciucco G, Ferrara GB. Palmisano GL, et al. Among authors: pistillo mp. Hum Immunol. 2002 Nov;63(11):969-76. doi: 10.1016/s0198-8859(02)00642-0. Hum Immunol. 2002. PMID: 12392849
91 results