Küppers R - Search Results

1

Lack of somatic hypermutation of IG V(H) genes in lymphoid malignancies with t(2;14)(p13;q32) translocation involving the BCL11A gene.

Küppers R, Sonoki T, Satterwhite E, Gesk S, Harder L, Oscier DG, Tucker PW, Dyer MJ, Siebert R. Küppers R, et al. Leukemia. 2002 May;16(5):937-9. doi: 10.1038/sj.leu.2402480. Leukemia. 2002. PMID: 11986957

2

B cells of chronic lymphatic leukemia express V genes in unmutated form.

Küppers R, Gause A, Rajewsky K. Küppers R, et al. Leuk Res. 1991;15(6):487-96. doi: 10.1016/0145-2126(91)90060-7. Leuk Res. 1991. PMID: 1713635

3

Analysis of immunoglobulin gene rearrangements in single B cells.

Ehlich A, Küppers R. Ehlich A, et al. Among authors: kuppers r. Curr Opin Immunol. 1995 Apr;7(2):281-4. doi: 10.1016/0952-7915(95)80016-6. Curr Opin Immunol. 1995. PMID: 7546390 Review.

4

Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.

Klein U, Küppers R, Rajewsky K. Klein U, et al. Among authors: kuppers r. J Exp Med. 1994 Oct 1;180(4):1383-93. doi: 10.1084/jem.180.4.1383. J Exp Med. 1994. PMID: 7931072 Free PMC article.

5

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life.

Klein U, Küppers R, Rajewsky K. Klein U, et al. Among authors: kuppers r. Eur J Immunol. 1993 Dec;23(12):3272-7. doi: 10.1002/eji.1830231232. Eur J Immunol. 1993. PMID: 8258343

6

Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections.

Küppers R, Zhao M, Hansmann ML, Rajewsky K. Küppers R, et al. EMBO J. 1993 Dec 15;12(13):4955-67. doi: 10.1002/j.1460-2075.1993.tb06189.x. EMBO J. 1993. PMID: 8262038 Free PMC article.

7

Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes.

Klein U, Klein G, Ehlin-Henriksson B, Rajewsky K, Küppers R. Klein U, et al. Among authors: kuppers r. Mol Med. 1995 Jul;1(5):495-505. Mol Med. 1995. PMID: 8529116 Free PMC article.

8

Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enhancers) abolishes somatic hypermutation in the human.

Küppers R, Hajadi M, Plank L, Rajewsky K, Hansmann ML. Küppers R, et al. Eur J Immunol. 1996 Aug;26(8):1794-800. doi: 10.1002/eji.1830260820. Eur J Immunol. 1996. PMID: 8765023

9

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

Kanzler H, Küppers R, Hansmann ML, Rajewsky K. Kanzler H, et al. Among authors: kuppers r. J Exp Med. 1996 Oct 1;184(4):1495-505. doi: 10.1084/jem.184.4.1495. J Exp Med. 1996. PMID: 8879220 Free PMC article.

10

Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression.

Küppers R, Rajewsky K, Hansmann ML. Küppers R, et al. Eur J Immunol. 1997 Jun;27(6):1398-405. doi: 10.1002/eji.1830270616. Eur J Immunol. 1997. PMID: 9209491

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